Magnesium in PDB 2qwl: Crystal Structure of Bovine HSC70 (1-394AA)in the Adp State

The structure of Crystal Structure of Bovine HSC70 (1-394AA)in the Adp State, PDB code: 2qwl was solved by J.Jiang, E.G.Maes, L.Wang, A.B.Taylor, A.P.Hinck, E.M.Lafer, R.Sousa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	35.16 / 1.75
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	73.306, 77.962, 75.320, 90.00, 101.46, 90.00
R / Rfree (%)	17.6 / 20.9

The structure of Crystal Structure of Bovine HSC70 (1-394AA)in the Adp State also contains other interesting chemical elements:

Sodium

(Na)

4 atoms

The binding sites of Magnesium atom in the Crystal Structure of Bovine HSC70 (1-394AA)in the Adp State (pdb code 2qwl). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Bovine HSC70 (1-394AA)in the Adp State, PDB code: 2qwl:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Bovine HSC70 (1-394AA)in the Adp State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Bovine HSC70 (1-394AA)in the Adp State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg587 b:10.2 occ:1.00 O A:HOH683 2.0 6.4 1.0 O A:HOH686 2.1 8.4 1.0 O A:HOH654 2.1 9.4 1.0 O A:HOH722 2.1 9.0 1.0 O3B A:ADP486 2.1 7.9 1.0 O A:HOH596 2.2 10.6 1.0 PB A:ADP486 3.3 8.7 1.0 NA A:NA589 3.4 8.4 1.0 O2B A:ADP486 3.5 10.2 1.0 O1A A:ADP486 3.8 6.9 1.0 OD2 A:ASP10 4.0 14.2 1.0 OD1 A:ASP10 4.1 12.9 1.0 OE1 A:GLU175 4.1 13.2 1.0 OD2 A:ASP199 4.1 12.8 1.0 OD1 A:ASP199 4.2 11.7 1.0 O3A A:ADP486 4.4 6.0 1.0 NA A:NA590 4.4 15.1 1.0 O1B A:ADP486 4.4 6.7 1.0 CG A:ASP10 4.5 12.4 1.0 CG A:ASP199 4.6 12.8 1.0 O A:HOH645 4.7 6.0 1.0 PA A:ADP486 4.8 6.4 1.0 CD A:GLU175 4.8 11.7 1.0 CA A:GLY12 4.9 9.8 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Bovine HSC70 (1-394AA)in the Adp State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Bovine HSC70 (1-394AA)in the Adp State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg687 b:6.9 occ:1.00 O B:HOH785 2.0 5.9 1.0 O B:HOH828 2.0 6.0 1.0 O B:HOH738 2.1 7.6 1.0 O3B B:ADP486 2.1 5.7 1.0 O B:HOH904 2.1 11.7 1.0 O B:HOH691 2.2 9.1 1.0 PB B:ADP486 3.3 5.4 1.0 NA B:NA689 3.4 6.7 1.0 O2B B:ADP486 3.6 6.4 1.0 O1A B:ADP486 3.9 4.5 1.0 OD2 B:ASP10 4.1 13.4 1.0 OD2 B:ASP199 4.2 11.5 1.0 OE1 B:GLU175 4.2 13.9 1.0 OD1 B:ASP199 4.2 11.8 1.0 OD1 B:ASP10 4.2 13.6 1.0 O3A B:ADP486 4.3 6.1 1.0 O1B B:ADP486 4.4 5.3 1.0 NA B:NA690 4.4 13.2 1.0 CG B:ASP10 4.6 12.6 1.0 CG B:ASP199 4.6 12.7 1.0 PA B:ADP486 4.8 5.8 1.0 O B:HOH751 4.8 5.8 1.0 CD B:GLU175 4.9 12.3 1.0 CA B:GLY12 4.9 9.8 1.0

J.Jiang, E.G.Maes, A.B.Taylor, L.Wang, A.P.Hinck, E.M.Lafer, R.Sousa. Structural Basis of J Cochaperone Binding and Regulation of HSP70. Mol.Cell V. 28 422 2007.
ISSN: ISSN 1097-2765
PubMed: 17996706
DOI: 10.1016/J.MOLCEL.2007.08.022