Magnesium in PDB 2qwm: Crystal Structure of Bovine HSC70 (1-394AA)in the Adp*VI State

The structure of Crystal Structure of Bovine HSC70 (1-394AA)in the Adp*VI State, PDB code: 2qwm was solved by J.Jiang, E.G.Maes, L.Wang, A.B.Taylor, A.P.Hinck, E.M.Lafer, R.Sousa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	36.06 / 1.86
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	73.336, 77.841, 75.793, 90.00, 101.53, 90.00
R / Rfree (%)	18.8 / 22.4

The structure of Crystal Structure of Bovine HSC70 (1-394AA)in the Adp*VI State also contains other interesting chemical elements:

Vanadium	(V)	2 atoms
Sodium	(Na)	4 atoms

The binding sites of Magnesium atom in the Crystal Structure of Bovine HSC70 (1-394AA)in the Adp*VI State (pdb code 2qwm). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Bovine HSC70 (1-394AA)in the Adp*VI State, PDB code: 2qwm:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Bovine HSC70 (1-394AA)in the Adp*VI State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Bovine HSC70 (1-394AA)in the Adp*VI State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg587 b:8.3 occ:1.00 O1 A:VO4491 1.8 12.5 1.0 O3B A:ADP486 1.9 11.6 1.0 O A:HOH727 2.0 3.6 1.0 O A:HOH656 2.1 6.0 1.0 O A:HOH600 2.2 3.4 1.0 V A:VO4491 3.3 17.9 1.0 PB A:ADP486 3.4 9.7 1.0 NA A:NA589 3.5 2.0 1.0 O2 A:VO4491 3.7 9.9 1.0 O1A A:ADP486 3.8 7.8 1.0 O2B A:ADP486 4.0 16.7 1.0 NA A:NA590 4.0 9.4 1.0 OD1 A:ASP199 4.1 12.8 1.0 OD2 A:ASP199 4.2 13.2 1.0 O3A A:ADP486 4.3 8.7 1.0 O1B A:ADP486 4.3 10.3 1.0 OD2 A:ASP10 4.4 15.6 1.0 OE1 A:GLU175 4.4 13.4 1.0 OD1 A:ASP10 4.5 13.3 1.0 O4 A:VO4491 4.5 9.8 1.0 CG A:ASP199 4.6 12.6 1.0 PA A:ADP486 4.7 6.1 1.0 O3 A:VO4491 4.7 11.8 1.0 O A:HOH616 4.8 6.7 1.0 O A:HOH597 4.9 8.3 1.0 CG A:ASP10 4.9 13.3 1.0 CA A:GLY338 5.0 11.9 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Bovine HSC70 (1-394AA)in the Adp*VI State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Bovine HSC70 (1-394AA)in the Adp*VI State within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg687 b:7.0 occ:1.00 O1 B:VO4491 1.9 10.1 1.0 O B:HOH803 2.0 5.8 1.0 O B:HOH840 2.0 4.4 1.0 O3B B:ADP486 2.0 11.6 1.0 O B:HOH712 2.1 2.0 1.0 V B:VO4491 3.3 17.3 1.0 PB B:ADP486 3.5 8.7 1.0 NA B:NA689 3.5 2.0 1.0 O2 B:VO4491 3.6 8.6 1.0 O1A B:ADP486 3.9 5.9 1.0 NA B:NA690 4.0 7.9 1.0 OD1 B:ASP199 4.1 10.2 1.0 OD2 B:ASP199 4.1 11.2 1.0 O2B B:ADP486 4.1 14.4 1.0 OE1 B:GLU175 4.3 13.3 1.0 O1B B:ADP486 4.3 8.2 1.0 OD2 B:ASP10 4.4 15.8 1.0 O4 B:VO4491 4.4 9.0 1.0 O3A B:ADP486 4.4 6.6 1.0 OD1 B:ASP10 4.5 13.4 1.0 CG B:ASP199 4.6 11.5 1.0 O3 B:VO4491 4.7 9.1 1.0 PA B:ADP486 4.8 5.1 1.0 O B:HOH716 4.8 5.6 1.0 O B:HOH707 4.9 8.5 1.0 CG B:ASP10 4.9 12.6 1.0 CD B:GLU175 4.9 12.5 1.0

J.Jiang, E.G.Maes, A.B.Taylor, L.Wang, A.P.Hinck, E.M.Lafer, R.Sousa. Structural Basis of J Cochaperone Binding and Regulation of HSP70. Mol.Cell V. 28 422 2007.
ISSN: ISSN 1097-2765
PubMed: 17996706
DOI: 10.1016/J.MOLCEL.2007.08.022