Atomistry » Magnesium » PDB 2rex-2uxd » 2rio
Atomistry »
  Magnesium »
    PDB 2rex-2uxd »
      2rio »

Magnesium in PDB 2rio: Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation of Non-Conventional Splicing

Enzymatic activity of Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation of Non-Conventional Splicing

All present enzymatic activity of Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation of Non-Conventional Splicing:
2.7.11.1;

Protein crystallography data

The structure of Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation of Non-Conventional Splicing, PDB code: 2rio was solved by K.P.Lee, M.Dey, D.Neculai, C.Cao, T.E.Dever, F.Sicheri, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 19.83 / 2.40
Space group P 65
Cell size a, b, c (Å), α, β, γ (°) 130.307, 130.307, 175.011, 90.00, 90.00, 120.00
R / Rfree (%) 22.2 / 26.6

Other elements in 2rio:

The structure of Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation of Non-Conventional Splicing also contains other interesting chemical elements:

Strontium (Sr) 2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation of Non-Conventional Splicing (pdb code 2rio). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation of Non-Conventional Splicing, PDB code: 2rio:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 2rio

Go back to Magnesium Binding Sites List in 2rio
Magnesium binding site 1 out of 2 in the Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation of Non-Conventional Splicing


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation of Non-Conventional Splicing within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1102

b:29.0
occ:1.00
 O1A A:ADP1101 2.0 18.4 1.0
OD2 A:ASP171 2.0 23.2 1.0
O3B A:ADP1101 2.0 25.7 1.0
OD1 A:ASN145 2.2 18.5 1.0
CG A:ASP171 3.2 29.0 1.0
CG A:ASN145 3.2 25.2 1.0
PB A:ADP1101 3.3 25.0 1.0
PA A:ADP1101 3.4 19.9 1.0
ND2 A:ASN145 3.6 24.9 1.0
O3A A:ADP1101 3.7 20.5 1.0
O2B A:ADP1101 3.7 24.6 1.0
CB A:ASP171 3.9 27.1 1.0
SR A:SR1103 4.2 34.5 1.0
O5' A:ADP1101 4.2 23.6 1.0
OD1 A:ASP171 4.2 25.1 1.0
O2A A:ADP1101 4.5 20.9 1.0
CB A:ASN145 4.5 19.5 1.0
O1B A:ADP1101 4.5 27.4 1.0
O A:GLN144 4.7 23.9 1.0
C5' A:ADP1101 4.7 22.1 1.0
CA A:ASN145 4.8 21.5 1.0
OD2 A:ASP140 4.9 26.5 1.0
C A:GLN144 5.0 23.6 1.0

Magnesium binding site 2 out of 2 in 2rio

Go back to Magnesium Binding Sites List in 2rio
Magnesium binding site 2 out of 2 in the Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation of Non-Conventional Splicing


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation of Non-Conventional Splicing within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg2102

b:26.8
occ:1.00
 O1A B:ADP2101 2.1 18.6 1.0
O3B B:ADP2101 2.1 21.7 1.0
OD2 B:ASP171 2.2 18.9 1.0
OD1 B:ASN145 2.2 20.7 1.0
CG B:ASN145 3.1 24.3 1.0
CG B:ASP171 3.2 26.1 1.0
ND2 B:ASN145 3.3 19.2 1.0
PB B:ADP2101 3.4 20.7 1.0
PA B:ADP2101 3.4 18.6 1.0
O3A B:ADP2101 3.8 19.3 1.0
O2B B:ADP2101 3.9 22.4 1.0
CB B:ASP171 3.9 24.8 1.0
SR B:SR2103 4.1 37.0 1.0
OD1 B:ASP171 4.2 20.2 1.0
O5' B:ADP2101 4.2 18.7 1.0
CB B:ASN145 4.5 21.9 1.0
O2A B:ADP2101 4.6 18.4 1.0
O1B B:ADP2101 4.6 25.7 1.0
C5' B:ADP2101 4.8 19.6 1.0
O B:GLN144 4.9 25.1 1.0
CA B:ASN145 4.9 23.0 1.0
OD2 B:ASP140 4.9 38.0 1.0
N B:ASN145 5.0 24.1 1.0

Reference:

K.P.Lee, M.Dey, D.Neculai, C.Cao, T.E.Dever, F.Sicheri. Structure of the Dual Enzyme IRE1 Reveals the Basis For Catalysis and Regulation in Nonconventional Rna Splicing. Cell(Cambridge,Mass.) V. 132 89 2008.
ISSN: ISSN 0092-8674
PubMed: 18191223
DOI: 10.1016/J.CELL.2007.10.057
Page generated: Wed Aug 14 03:24:15 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy