Magnesium in PDB 2uxq: Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila: Biochemical Properties and Crystal Structure Analysis

The structure of Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila: Biochemical Properties and Crystal Structure Analysis, PDB code: 2uxq was solved by A.-E.Fedoy, N.Yang, A.Martinez, H.-K.S.Leiros, I.H.Steen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 1.75
Space group	P 1
Cell size a, b, c (Å), α, β, γ (°)	59.324, 73.279, 126.413, 98.90, 98.98, 113.88
R / Rfree (%)	14.6 / 18.9

The binding sites of Magnesium atom in the Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila: Biochemical Properties and Crystal Structure Analysis (pdb code 2uxq). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila: Biochemical Properties and Crystal Structure Analysis, PDB code: 2uxq:

Magnesium binding site 1 out of 1 in the Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila: Biochemical Properties and Crystal Structure Analysis


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila: Biochemical Properties and Crystal Structure Analysis within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1407 b:40.0 occ:1.00 OD1 A:ASP272 2.6 18.4 1.0 OD2 A:ASP276 2.8 17.2 1.0 O A:HOH2345 2.8 19.5 1.0 OD2 B:ASP249 3.1 23.9 0.0 O A:HOH2363 3.2 26.7 1.0 CG B:ASP249 3.5 18.6 1.0 C1 A:GOL1405 3.6 53.5 1.0 CB B:ASP249 3.6 16.1 1.0 CG A:ASP276 3.6 15.3 1.0 CG A:ASP272 3.7 15.7 1.0 OD1 A:ASP276 3.7 15.3 1.0 C3 A:GOL1405 3.7 51.4 1.0 O A:ASP272 3.9 12.6 1.0 C2 A:GOL1405 4.0 52.1 1.0 O A:HOH2155 4.0 40.3 1.0 NZ B:LYS209 4.1 23.0 0.8 OD2 A:ASP272 4.2 18.1 1.0 OD1 B:ASP249 4.5 18.7 1.0 C A:ASP272 4.6 12.4 1.0 O A:HOH2346 4.7 34.5 1.0 O3 A:GOL1405 4.8 49.9 1.0 O1 A:GOL1405 4.8 55.0 1.0 CB A:ASP276 4.9 11.1 1.0 CA A:ASP272 4.9 12.2 1.0 CB A:ASP272 4.9 10.6 1.0

A.-E.Fedoy, N.Yang, A.Martinez, H.-K.S.Leiros, I.H.Steen. Structural and Functional Properties of Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila Reveal A Cold -Active Enzyme with An Unusual High Thermal J.Mol.Biol. V. 372 130 2007.
ISSN: ISSN 0022-2836
PubMed: 17632124
DOI: 10.1016/J.JMB.2007.06.040