Magnesium in PDB 2uxr: Complex with Isocitrate and the Protein Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila

The structure of Complex with Isocitrate and the Protein Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila, PDB code: 2uxr was solved by A.-E.Fedoy, N.Yang, A.Martinez, H.-K.S.Leiros, I.H.Steen, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.3
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	58.560, 121.740, 273.770, 90.00, 90.00, 90.00
R / Rfree (%)	19.5 / 25.9

The binding sites of Magnesium atom in the Complex with Isocitrate and the Protein Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila (pdb code 2uxr). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Complex with Isocitrate and the Protein Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila, PDB code: 2uxr:
Jump to Magnesium binding site number: 1; 2; 3;

Magnesium binding site 1 out of 3 in the Complex with Isocitrate and the Protein Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Complex with Isocitrate and the Protein Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1405 b:18.1 occ:1.00 OD1 A:ASP272 2.0 16.8 1.0 O1 A:ICT1403 2.0 15.9 1.0 OD2 B:ASP249 2.1 13.3 1.0 O A:HOH2102 2.2 19.8 1.0 O7 A:ICT1403 2.3 12.1 1.0 C1 A:ICT1403 2.9 16.1 1.0 CG A:ASP272 3.1 10.2 1.0 C2 A:ICT1403 3.2 11.4 1.0 CG B:ASP249 3.3 15.2 1.0 OD2 A:ASP272 3.7 9.4 1.0 O A:ALA304 3.8 23.8 1.0 CB B:ASP249 3.9 14.6 1.0 O A:ASP272 3.9 13.8 1.0 NH1 A:ARG108 4.1 14.3 1.0 O2 A:ICT1403 4.1 17.2 1.0 C6 A:ICT1403 4.1 11.2 1.0 OD2 A:ASP276 4.2 19.4 1.0 NZ B:LYS209 4.2 10.5 1.0 OD1 A:ASP276 4.2 12.9 1.0 C3 A:ICT1403 4.3 12.1 1.0 CB A:ASP272 4.3 11.1 1.0 O A:HOH2103 4.3 24.1 1.0 OD1 B:ASP249 4.3 13.7 1.0 O6 A:ICT1403 4.4 9.1 1.0 CG A:ASP276 4.4 15.1 1.0 CA A:ASP272 4.4 12.3 1.0 O5 A:ICT1403 4.4 8.9 1.0 C A:ASP272 4.5 13.3 1.0 NH1 A:ARG131 4.7 11.5 1.0 O B:HOH2053 4.9 25.1 1.0

Magnesium binding site 2 out of 3 in the Complex with Isocitrate and the Protein Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Complex with Isocitrate and the Protein Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1406 b:24.7 occ:1.00 O1 A:ICT1404 2.5 56.2 1.0 C1 A:ICT1404 3.7 53.6 1.0 N A:VAL308 3.8 17.4 1.0 CA A:VAL308 4.0 16.1 1.0 O2 A:ICT1404 4.0 50.0 1.0 N A:THR307 4.2 18.1 1.0 CA A:GLY306 4.2 18.5 1.0 C A:GLY306 4.3 18.6 1.0 N A:GLN309 4.3 17.9 1.0 O6 A:ICT1404 4.4 50.6 1.0 N A:GLY306 4.7 20.4 1.0 C A:VAL308 4.7 17.4 1.0 C A:THR307 4.8 17.3 1.0 C2 A:ICT1404 4.9 52.2 1.0 O A:GLY306 4.9 18.6 1.0

Magnesium binding site 3 out of 3 in the Complex with Isocitrate and the Protein Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Complex with Isocitrate and the Protein Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1398 b:32.3 occ:1.00 O5 B:ICT1397 2.0 34.4 1.0 OD1 B:ASP272 2.1 21.9 1.0 OD2 A:ASP249 2.3 14.7 1.0 O4 B:ICT1397 2.4 28.7 1.0 C6 B:ICT1397 3.2 36.0 1.0 CG B:ASP272 3.3 21.5 1.0 CG A:ASP249 3.4 18.9 1.0 OD1 B:ASP276 3.4 26.1 1.0 C5 B:ICT1397 3.5 30.8 1.0 O B:ASP272 3.5 18.7 1.0 CB A:ASP249 3.7 18.6 1.0 NH1 B:ARG108 3.8 24.0 1.0 CG B:ASP276 3.9 25.0 1.0 OD2 B:ASP276 3.9 27.4 1.0 O6 B:ICT1397 4.0 37.9 1.0 O B:ALA304 4.0 50.9 1.0 OD2 B:ASP272 4.0 24.4 1.0 C B:ASP272 4.2 18.6 1.0 C4 B:ICT1397 4.2 32.6 1.0 CA B:ASP272 4.2 19.8 1.0 CB B:ASP272 4.2 20.5 1.0 C3 B:ICT1397 4.3 32.3 1.0 NZ A:LYS209 4.4 24.8 1.0 OD1 A:ASP249 4.5 17.6 1.0 O3 B:ICT1397 4.5 33.4 1.0 NH1 B:ARG131 4.6 17.0 1.0 O B:HOH2069 4.6 22.8 1.0 OG B:SER275 4.8 23.9 1.0 O7 B:ICT1397 4.9 23.2 1.0 CZ B:ARG108 4.9 23.7 1.0 CB B:ASP276 5.0 24.0 1.0

A.-E.Fedoy, N.Yang, A.Martinez, H.-K.S.Leiros, I.H.Steen. Structural and Functional Properties of Isocitrate Dehydrogenase From the Psychrophilic Bacterium Desulfotalea Psychrophila Reveal A Cold -Active Enzyme with An Unusual High Thermal J.Mol.Biol. V. 372 130 2007.
ISSN: ISSN 0022-2836
PubMed: 17632124
DOI: 10.1016/J.JMB.2007.06.040