Magnesium in the structure of Crystal Structure of Human Recq-Like Dna Helicase (pdb 2v1x)

The binding sites of Magnesium atom in the structure of Crystal Structure of Human Recq-Like Dna Helicase (pdb code 2v1x). This binding sites where shown with 5.0 Angstroms radius around Magnesium atom. The 2v1x structure was solved by A.C.W.PIKE, B.SHRESTHA, N.BURGESS-BROWN, O.KING, E.UGOCHUKWU, S.WATT, A.EDWARDS, C.H.ARROWSMITH, J.WEIGELT, M.SUNDSTROM, O.GILEADI, with X-Ray Crystallography technique, brief refinement statistics is given in the table below: Resolution (A) 45.0-2.0 Space group P1211 a (A) 83.229 b (A) 97.647 c (A) 85.849 alpha (°) 90.00 beta (°) 104.50 gamma (°) 90.00 Rfactor (%) 23.2 Rfree (%) 27.8 Magnesium Binding Sites: Magnesium binding site 1 out of 2 in 2v1x Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 1 of Magnesium in the PDB 2v1x. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Magnesium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: A: Lys119, A: Ser120, A: Asp219, A: Glu220, A: Adp1593, A: Hoh2017, A: Hoh2018, A: Hoh2033, A: Hoh2034, A: Hoh2144, conact list: Atom Atom Distance (A) Mg CB A:Lys119 4.81 Mg CE A:Lys119 4.65 Mg OG A:Ser120 3.69 Mg OD2 A:Asp219 4.10 Mg OD1 A:Asp219 4.26 Mg CG A:Asp219 4.59 Mg OE2 A:Glu220 4.49 Mg O3B A:Adp1593 4.27 Mg PA A:Adp1593 4.52 Mg O2A A:Adp1593 4.32 Mg O1B A:Adp1593 3.46 Mg PB A:Adp1593 3.14 Mg O2B A:Adp1593 1.86 Mg O3A A:Adp1593 4.18 Mg O1A A:Adp1593 4.55 Mg O A:Hoh2017 3.99 Mg O A:Hoh2018 2.11 Mg O A:Hoh2033 1.89 Mg O A:Hoh2034 2.25 Mg O A:Hoh2144 2.47 interactive model: Magnesium binding site 2 out of 2 in 2v1x Click to enlarge Click to enlarge Mono- and Stereo- picture of 5.0 Angstrom coordination sphere 2 of Magnesium in the PDB 2v1x. Coordination sphere was calculated for all residues within 5.0 Angstroms distance from the central Magnesium atom, shown by VdW sphere Residues shown as a stick model or VDW spheres: B: Lys119, B: Ser120, B: Gln147, B: Asp219, B: Glu220, B: Adp1593, B: Hoh2026, B: Hoh2027, B: Hoh2037, B: Hoh2038, B: Hoh2162, B: Hoh2165, B: Hoh2166, conact list: Atom Atom Distance (A) Mg CB B:Lys119 4.87 Mg CE B:Lys119 4.67 Mg OG B:Ser120 4.19 Mg NE2 B:Gln147 4.72 Mg OD2 B:Asp219 3.94 Mg OD1 B:Asp219 4.18 Mg CG B:Asp219 4.48 Mg OE1 B:Glu220 4.00 Mg O3B B:Adp1593 4.33 Mg PA B:Adp1593 4.68 Mg O2A B:Adp1593 4.60 Mg O1B B:Adp1593 3.60 Mg PB B:Adp1593 3.24 Mg O2B B:Adp1593 1.98 Mg O3A B:Adp1593 4.27 Mg O1A B:Adp1593 4.76 Mg O B:Hoh2026 4.26 Mg O B:Hoh2027 2.27 Mg O B:Hoh2037 2.00 Mg O B:Hoh2038 2.03 Mg O B:Hoh2162 2.51 Mg O B:Hoh2165 1.87 Mg O B:Hoh2166 4.98 interactive model: