Magnesium in PDB 2vxt: Crystal Structure of Human Il-18 Complexed to Murine Reference Antibody 125-2H Fab

The structure of Crystal Structure of Human Il-18 Complexed to Murine Reference Antibody 125-2H Fab, PDB code: 2vxt was solved by M.A.Argiriadi, T.Xiang, C.Wu, T.Ghayur, D.W.Borhani, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	31.16 / 1.49
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	44.345, 62.435, 104.734, 90.00, 100.39, 90.00
R / Rfree (%)	16.2 / 19.6

The structure of Crystal Structure of Human Il-18 Complexed to Murine Reference Antibody 125-2H Fab also contains other interesting chemical elements:

Chlorine

(Cl)

2 atoms

The binding sites of Magnesium atom in the Crystal Structure of Human Il-18 Complexed to Murine Reference Antibody 125-2H Fab (pdb code 2vxt). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Il-18 Complexed to Murine Reference Antibody 125-2H Fab, PDB code: 2vxt:

Magnesium binding site 1 out of 1 in the Crystal Structure of Human Il-18 Complexed to Murine Reference Antibody 125-2H Fab


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Il-18 Complexed to Murine Reference Antibody 125-2H Fab within 5.0Å range: probe atom residue distance (Å) B Occ I:Mg1194 b:19.0 occ:1.00 O I:HOH2070 2.0 23.4 1.0 O I:HOH2042 2.0 20.0 1.0 O I:HOH2069 2.0 18.1 1.0 OD1 I:ASP134 4.0 19.7 1.0 OD2 I:ASP134 4.1 19.0 1.0 O I:HOH2068 4.4 49.6 1.0 OH I:TYR156 4.5 18.4 1.0 CG I:ASP134 4.5 18.5 1.0 OE2 I:GLU113 4.6 17.0 1.0 O I:HOH2092 4.6 28.8 1.0 O I:HOH2093 5.0 24.4 1.0

M.A.Argiriadi, T.Xiang, C.Wu, T.Ghayur, D.W.Borhani. Unusual Water-Mediated Antigenic Recognition of the Proinflammatory Cytokine Interleukin-18. J.Biol.Chem. V. 284 24478 2009.
ISSN: ISSN 0021-9258
PubMed: 19553661
DOI: 10.1074/JBC.M109.023887