Magnesium in PDB 2w2t: RAC2 (G12V) in Complex with Gdp

The structure of RAC2 (G12V) in Complex with Gdp, PDB code: 2w2t was solved by O.Opaleye, T.D.Bunney, S.M.Roe, L.H.Pearl, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	54.03 / 1.95
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	42.205, 98.106, 108.064, 90.00, 90.00, 90.00
R / Rfree (%)	20.7 / 25.4

The binding sites of Magnesium atom in the RAC2 (G12V) in Complex with Gdp (pdb code 2w2t). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the RAC2 (G12V) in Complex with Gdp, PDB code: 2w2t:

Magnesium binding site 1 out of 1 in the RAC2 (G12V) in Complex with Gdp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of RAC2 (G12V) in Complex with Gdp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1180 b:29.4 occ:1.00 OG1 A:THR17 2.1 24.0 1.0 O A:HOH2058 2.1 23.9 1.0 O A:HOH2135 2.2 26.9 1.0 O A:HOH2013 2.2 26.4 1.0 O1B A:GDP1181 2.2 27.9 1.0 O A:HOH2138 2.3 23.1 1.0 CB A:THR17 3.1 27.8 1.0 PB A:GDP1181 3.3 28.8 1.0 O2B A:GDP1181 3.4 30.5 1.0 OD2 A:ASP57 3.9 23.1 1.0 N A:THR17 3.9 27.0 1.0 CA A:THR17 4.0 28.2 1.0 O2A A:GDP1181 4.1 29.7 1.0 O A:HOH2060 4.2 24.6 1.0 CG2 A:THR17 4.2 25.2 1.0 O A:HOH2035 4.2 26.6 1.0 O A:HOH2067 4.2 30.0 1.0 O3B A:GDP1181 4.3 28.6 1.0 OD1 A:ASP57 4.3 26.5 1.0 O3A A:GDP1181 4.3 32.9 1.0 O A:HOH2038 4.4 24.6 1.0 O A:HOH2036 4.4 27.8 1.0 CG A:ASP57 4.5 25.5 1.0 PA A:GDP1181 4.6 30.5 1.0 O1A A:GDP1181 4.6 29.0 1.0 CE1 A:PHE37 4.7 23.9 1.0 O A:THR58 4.8 25.0 1.0 CD1 A:PHE37 4.8 27.7 1.0 CB A:LYS16 4.9 26.6 1.0 O A:HOH2136 4.9 32.6 1.0 NZ A:LYS16 5.0 23.6 1.0

T.D.Bunney, O.Opaleye, S.M.Roe, P.Vatter, R.W.Baxendale, C.Walliser, K.L.Everett, M.B.Josephs, C.Christow, F.Rodrigues-Lima, P.Gierschik, L.H.Pearl, M.Katan. Structural Insights Into Formation of An Active Signaling Complex Between Rac and Phospholipase C Gamma 2. Mol.Cell V. 34 223 2009.
ISSN: ISSN 1097-2765
PubMed: 19394299
DOI: 10.1016/J.MOLCEL.2009.02.023