Magnesium in PDB 2w5a: Human NEK2 Kinase Adp-Bound

All present enzymatic activity of Human NEK2 Kinase Adp-Bound:
2.7.11.1;

The structure of Human NEK2 Kinase Adp-Bound, PDB code: 2w5a was solved by I.Westwood, R.Bayliss, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	24.74 / 1.55
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	99.467, 57.103, 80.213, 90.00, 132.99, 90.00
R / Rfree (%)	17.2 / 19

The binding sites of Magnesium atom in the Human NEK2 Kinase Adp-Bound (pdb code 2w5a). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human NEK2 Kinase Adp-Bound, PDB code: 2w5a:

Magnesium binding site 1 out of 1 in the Human NEK2 Kinase Adp-Bound


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human NEK2 Kinase Adp-Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1281 b:25.1 occ:1.00 O2B A:ADP1280 2.2 27.6 1.0 O1A A:ADP1280 2.2 22.1 1.0 O A:HOH2207 2.3 25.5 1.0 O A:HOH2220 2.4 27.8 1.0 O A:HOH2221 2.4 26.8 1.0 O A:HOH2347 2.5 33.6 1.0 PB A:ADP1280 3.4 25.9 1.0 PA A:ADP1280 3.4 20.9 1.0 NH2 A:ARG164 3.5 58.6 1.0 O3A A:ADP1280 3.5 21.2 1.0 NZ A:LYS37 3.7 40.8 1.0 OD1 A:ASN146 3.8 24.3 1.0 O A:ASP159 4.0 29.3 1.0 O1B A:ADP1280 4.2 32.2 1.0 O A:HOH2226 4.2 31.6 1.0 OD1 A:ASP159 4.4 32.2 1.0 OD2 A:ASP159 4.4 30.8 1.0 O2A A:ADP1280 4.4 22.9 1.0 O A:HOH2348 4.5 49.3 1.0 O5' A:ADP1280 4.5 16.5 1.0 O3B A:ADP1280 4.6 30.6 1.0 CZ A:ARG164 4.6 56.8 1.0 CG A:ASP159 4.7 32.3 1.0 CG A:ASN146 4.7 25.2 1.0 CE A:LYS37 4.9 30.5 1.0 O A:PHE160 5.0 32.9 1.0

I.Westwood, D.M.Cheary, J.E.Baxter, M.W.Richards, R.L.Van Montfort, A.M.Fry, R.Bayliss. Insights Into the Conformational Variability and Regulation of Human NEK2 Kinase. J.Mol.Biol. V. 386 476 2009.
ISSN: ISSN 0022-2836
PubMed: 19124027
DOI: 10.1016/J.JMB.2008.12.033