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Atomistry » Magnesium » PDB 2vu9-2wb1 » 2w7x » |
Magnesium in PDB 2w7x: Cellular Inhibition of Checkpoint Kinase 2 and Potentiation of Cytotoxic Drugs By Novel CHK2 Inhibitor PV1019Enzymatic activity of Cellular Inhibition of Checkpoint Kinase 2 and Potentiation of Cytotoxic Drugs By Novel CHK2 Inhibitor PV1019
All present enzymatic activity of Cellular Inhibition of Checkpoint Kinase 2 and Potentiation of Cytotoxic Drugs By Novel CHK2 Inhibitor PV1019:
2.7.11.1; Protein crystallography data
The structure of Cellular Inhibition of Checkpoint Kinase 2 and Potentiation of Cytotoxic Drugs By Novel CHK2 Inhibitor PV1019, PDB code: 2w7x
was solved by
A.G.Jobson,
G.T.Lountos,
P.L.Lorenzi,
J.Llamas,
J.Connelly,
J.E.Tropea,
A.Onda,
S.Kondapaka,
G.Zhang,
N.J.Caplen,
J.H.Caredellina,
A.Monks,
C.Self,
D.S.Waugh,
R.H.Shoemaker,
Y.Pommier,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Cellular Inhibition of Checkpoint Kinase 2 and Potentiation of Cytotoxic Drugs By Novel CHK2 Inhibitor PV1019
(pdb code 2w7x). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Cellular Inhibition of Checkpoint Kinase 2 and Potentiation of Cytotoxic Drugs By Novel CHK2 Inhibitor PV1019, PDB code: 2w7x: Magnesium binding site 1 out of 1 in 2w7xGo back to Magnesium Binding Sites List in 2w7x
Magnesium binding site 1 out
of 1 in the Cellular Inhibition of Checkpoint Kinase 2 and Potentiation of Cytotoxic Drugs By Novel CHK2 Inhibitor PV1019
Mono view Stereo pair view
Reference:
A.G.Jobson,
G.T.Lountos,
P.L.Lorenzi,
J.Llamas,
J.Connelly,
D.Cerna,
J.E.Tropea,
A.Onda,
G.Zoppoli,
S.Kondapaka,
G.Zhang,
N.J.Caplen,
J.H.Cardellina,
S.S.Yoo,
A.Monks,
C.Self,
D.S.Waugh,
R.H.Shoemaker,
Y.Pommier.
Cellular Inhibition of CHK2 Kinase and Potentiation of Camptothecins and Radiation By the Novel CHK2 Inhibitor PV1019. J.Pharmacol.Exp.Ther. V. 331 816 2009.
Page generated: Mon Dec 14 07:43:36 2020
ISSN: ISSN 0022-3565 PubMed: 19741151 DOI: 10.1124/JPET.109.154997 |
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