Magnesium in PDB 2x6v: Crystal Structure of Human TBX5 in the Dna-Bound and Dna- Free Form

The structure of Crystal Structure of Human TBX5 in the Dna-Bound and Dna- Free Form, PDB code: 2x6v was solved by D.Ptchelkine, C.U.Stirnimann, C.Grimm, C.W.Mueller, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.707 / 2.20
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	118.240, 118.240, 243.000, 90.00, 90.00, 120.00
R / Rfree (%)	19.73 / 22.52

The binding sites of Magnesium atom in the Crystal Structure of Human TBX5 in the Dna-Bound and Dna- Free Form (pdb code 2x6v). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human TBX5 in the Dna-Bound and Dna- Free Form, PDB code: 2x6v:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Human TBX5 in the Dna-Bound and Dna- Free Form


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human TBX5 in the Dna-Bound and Dna- Free Form within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1239 b:61.4 occ:1.00 O A:SER86 2.7 40.8 1.0 OE1 A:GLU60 2.7 57.8 1.0 O A:HOH2005 3.1 37.5 1.0 CG A:LYS88 3.4 38.7 1.0 CD A:LYS88 3.6 39.2 1.0 C A:SER86 3.7 44.2 1.0 O A:HOH2007 3.7 42.2 1.0 CD2 A:HIS59 3.7 47.7 1.0 CD A:GLU60 3.8 61.4 1.0 CB A:SER86 3.8 37.7 1.0 CB A:LYS88 3.9 37.2 1.0 CE A:LYS88 4.0 40.3 1.0 CG A:GLU60 4.1 46.5 1.0 CB A:GLU60 4.2 40.5 1.0 CA A:SER86 4.2 41.1 1.0 N A:LYS88 4.2 35.2 1.0 N A:SER86 4.3 38.8 1.0 O A:HIS59 4.4 37.1 1.0 CG A:HIS59 4.5 47.6 1.0 CB A:HIS59 4.6 40.8 1.0 CA A:LYS88 4.7 34.0 1.0 N A:TYR87 4.7 35.9 1.0 C A:HIS59 4.7 41.0 1.0 C A:TYR87 4.8 35.9 1.0 NZ A:LYS88 4.8 47.6 1.0 NE2 A:HIS59 4.8 48.1 1.0 OE2 A:GLU60 4.8 58.7 1.0 OG A:SER86 4.9 43.1 1.0 CB A:PRO85 4.9 36.9 1.0 NE1 A:TRP64 4.9 37.4 1.0 CA A:TYR87 5.0 37.4 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Human TBX5 in the Dna-Bound and Dna- Free Form


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human TBX5 in the Dna-Bound and Dna- Free Form within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1233 b:72.3 occ:1.00 OE1 B:GLU60 2.9 72.2 1.0 N B:SER86 3.4 42.8 1.0 CD B:GLU60 3.8 67.5 1.0 OG B:SER86 3.9 63.7 1.0 CB B:SER86 3.9 42.6 1.0 CA B:PRO85 4.0 41.1 1.0 OE2 B:GLU60 4.0 78.8 1.0 O B:HOH2009 4.1 61.0 1.0 CB B:PRO85 4.2 39.4 1.0 C B:PRO85 4.2 49.5 1.0 CA B:SER86 4.3 49.3 1.0 CD2 B:LEU63 4.6 58.7 1.0 O B:SER86 4.8 47.8 1.0 CE2 B:PHE84 4.8 56.5 1.0 CZ B:PHE84 4.8 62.0 1.0

C.U.Stirnimann, D.Ptchelkine, C.Grimm, C.W.Muller. Structural Basis of TBX5-Dna Recognition: the T- Box Domain in Its Dna-Bound and -Unbound Form. J.Mol.Biol. V. 400 71 2010.
ISSN: ISSN 0022-2836
PubMed: 20450920
DOI: 10.1016/J.JMB.2010.04.052