Magnesium in PDB 2xdg: Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor.

The structure of Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor., PDB code: 2xdg was solved by A.C.W.Pike, A.Quigley, A.J.Barr, N.Burgess Brown, L.Shrestha, J.Yang, A.Chaikuad, M.Vollmar, J.R.C.Muniz, F.Von Delft, A.Edwards, C.H.Arrowsmith, J.Weigelt, C.Bountra, E.P.Carpenter, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	27.41 / 1.95
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	31.648, 31.648, 287.138, 90.00, 90.00, 120.00
R / Rfree (%)	16.5 / 22.3

The binding sites of Magnesium atom in the Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor. (pdb code 2xdg). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor., PDB code: 2xdg:
Jump to Magnesium binding site number: 1; 2; 3;

Magnesium binding site 1 out of 3 in the Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor. within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1122 b:31.3 occ:1.00 O A:HOH2001 2.2 38.1 1.0 OD2 A:ASP80 2.3 53.2 1.0 N A:MET0 2.9 49.3 1.0 CG A:ASP80 2.9 49.3 1.0 OD1 A:ASP80 3.0 48.6 1.0 C A:MET0 3.6 50.1 1.0 O A:MET0 3.6 46.6 1.0 CA A:MET0 3.6 51.8 1.0 CB A:ASP80 4.2 44.9 1.0 N A:LEU34 4.2 48.4 1.0 OD2 A:ASP37 4.3 45.4 1.0 OD1 A:ASP37 4.3 47.6 1.0 CG A:ASP37 4.7 43.5 1.0 CA A:LEU34 5.0 45.2 1.0

Magnesium binding site 2 out of 3 in the Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor. within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1122 b:35.2 occ:1.00 O B:HOH2024 1.9 39.1 1.0 NE2 B:HIS84 2.4 40.3 1.0 CD2 B:HIS84 3.3 38.4 1.0 CE1 B:HIS84 3.4 43.3 1.0 ND1 B:HIS84 4.5 42.3 1.0 CG B:HIS84 4.5 38.5 1.0 O B:ASP80 4.9 39.6 1.0

Magnesium binding site 3 out of 3 in the Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor. within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1123 b:34.8 occ:1.00 N B:MET0 2.2 48.7 1.0 O B:HOH2022 2.5 35.8 1.0 OD2 B:ASP80 2.8 56.6 1.0 OD1 B:ASP80 2.9 54.6 1.0 CA B:MET0 2.9 49.5 1.0 CG B:ASP80 3.2 50.6 1.0 C B:MET0 3.5 48.1 1.0 O B:MET0 4.0 47.5 1.0 OD2 B:ASP37 4.1 46.7 1.0 N B:LEU34 4.2 48.0 1.0 CB B:MET0 4.3 51.4 1.0 CB B:ASP80 4.7 44.5 1.0 CG B:ASP37 4.9 45.5 1.0 OD1 B:ASP37 4.9 48.9 1.0 O B:HOH2023 5.0 30.5 1.0

A.C.W.Pike, A.Quigley, A.J.Barr, N.Burgess Brown, L.Shrestha, J.Yang, A.Chaikuad, M.Vollmar, J.R.C.Muniz, F.Von Delft, A.Edwards, C.H.Arrowsmith, J.Weigelt, C.Bountra, E.P.Carpenter. Crystal Structure of the Extracellular Domain of Human Growth Hormone Releasing Hormone Receptor. To Be Published.