Atomistry » Magnesium » PDB 2xni-2xzs » 2xt6
Atomistry »
  Magnesium »
    PDB 2xni-2xzs »
      2xt6 »

Magnesium in PDB 2xt6: Crystal Structure of Mycobacterium Smegmatis Alpha-Ketoglutarate Decarboxylase Homodimer (Orthorhombic Form)

Enzymatic activity of Crystal Structure of Mycobacterium Smegmatis Alpha-Ketoglutarate Decarboxylase Homodimer (Orthorhombic Form)

All present enzymatic activity of Crystal Structure of Mycobacterium Smegmatis Alpha-Ketoglutarate Decarboxylase Homodimer (Orthorhombic Form):
4.1.1.71;

Protein crystallography data

The structure of Crystal Structure of Mycobacterium Smegmatis Alpha-Ketoglutarate Decarboxylase Homodimer (Orthorhombic Form), PDB code: 2xt6 was solved by T.Wagner, M.Bellinzoni, A.M.Wehenkel, H.M.O'hare, P.M.Alzari, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 40.12 / 2.74
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 151.990, 247.720, 79.980, 90.00, 90.00, 90.00
R / Rfree (%) 18.54 / 22.36

Other elements in 2xt6:

The structure of Crystal Structure of Mycobacterium Smegmatis Alpha-Ketoglutarate Decarboxylase Homodimer (Orthorhombic Form) also contains other interesting chemical elements:

Calcium (Ca) 2 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of Mycobacterium Smegmatis Alpha-Ketoglutarate Decarboxylase Homodimer (Orthorhombic Form) (pdb code 2xt6). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Mycobacterium Smegmatis Alpha-Ketoglutarate Decarboxylase Homodimer (Orthorhombic Form), PDB code: 2xt6:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 2xt6

Go back to Magnesium Binding Sites List in 2xt6
Magnesium binding site 1 out of 2 in the Crystal Structure of Mycobacterium Smegmatis Alpha-Ketoglutarate Decarboxylase Homodimer (Orthorhombic Form)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Mycobacterium Smegmatis Alpha-Ketoglutarate Decarboxylase Homodimer (Orthorhombic Form) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg2002

b:41.3
occ:1.00
 O A:HOH3017 2.0 46.2 1.0
O2A A:TPP2001 2.0 57.0 1.0
OD1 A:ASP645 2.1 39.8 1.0
OD1 A:ASN678 2.1 47.6 1.0
O A:ILE680 2.2 48.6 1.0
O2B A:TPP2001 2.3 57.9 1.0
CG A:ASN678 3.2 59.9 1.0
PB A:TPP2001 3.2 61.6 1.0
PA A:TPP2001 3.2 50.4 1.0
CG A:ASP645 3.2 46.3 1.0
O3A A:TPP2001 3.3 66.7 1.0
C A:ILE680 3.4 51.0 1.0
O3B A:TPP2001 3.6 60.1 1.0
ND2 A:ASN678 3.6 56.4 1.0
N A:ASP645 3.9 45.6 1.0
OD2 A:ASP645 4.0 57.3 1.0
O7 A:TPP2001 4.2 74.4 1.0
N A:ILE680 4.3 48.2 1.0
CB A:ASP645 4.3 45.0 1.0
N A:ASN678 4.3 49.1 1.0
O1A A:TPP2001 4.3 54.6 1.0
O A:VAL676 4.3 52.5 1.0
N A:GLY681 4.3 47.0 1.0
CA A:GLY681 4.4 46.8 1.0
N A:ALA646 4.4 35.6 1.0
CA A:ILE680 4.4 48.7 1.0
CB A:ASN678 4.5 44.1 1.0
CA A:ASP645 4.5 43.0 1.0
O A:HOH3054 4.6 38.0 1.0
CG2 A:ILE680 4.7 52.7 1.0
C A:GLY644 4.7 49.6 1.0
O1B A:TPP2001 4.7 49.7 1.0
CA A:GLY644 4.7 46.5 1.0
CA A:ASN678 4.8 47.2 1.0
C A:ASN678 4.9 51.0 1.0
N A:GLN679 4.9 47.0 1.0

Magnesium binding site 2 out of 2 in 2xt6

Go back to Magnesium Binding Sites List in 2xt6
Magnesium binding site 2 out of 2 in the Crystal Structure of Mycobacterium Smegmatis Alpha-Ketoglutarate Decarboxylase Homodimer (Orthorhombic Form)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Mycobacterium Smegmatis Alpha-Ketoglutarate Decarboxylase Homodimer (Orthorhombic Form) within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg2002

b:32.1
occ:1.00
 O2A B:TPP2001 2.0 35.1 1.0
O B:ILE680 2.0 43.2 1.0
OD1 B:ASN678 2.1 47.7 1.0
OD1 B:ASP645 2.2 47.5 1.0
O B:HOH3062 2.3 40.8 1.0
O2B B:TPP2001 2.4 34.5 1.0
CG B:ASP645 2.9 49.3 1.0
OD2 B:ASP645 3.1 48.5 1.0
CG B:ASN678 3.2 60.6 1.0
C B:ILE680 3.3 45.2 1.0
PA B:TPP2001 3.3 44.5 1.0
PB B:TPP2001 3.3 45.2 1.0
O3A B:TPP2001 3.4 33.3 1.0
ND2 B:ASN678 3.7 51.8 1.0
O3B B:TPP2001 3.9 36.8 1.0
N B:ASP645 4.0 41.2 1.0
N B:ILE680 4.1 41.9 1.0
N B:GLY681 4.1 42.2 1.0
CA B:GLY681 4.2 42.2 1.0
O7 B:TPP2001 4.2 43.1 1.0
CB B:ASP645 4.3 42.4 1.0
CA B:ILE680 4.3 41.9 1.0
N B:ASN678 4.3 42.9 1.0
N B:ALA646 4.4 38.4 1.0
O1A B:TPP2001 4.4 32.9 1.0
O B:HOH3021 4.5 41.6 1.0
CB B:ASN678 4.5 42.0 1.0
O B:VAL676 4.5 46.2 1.0
CG2 B:ILE680 4.6 47.1 1.0
CA B:ASP645 4.6 40.1 1.0
N B:GLN679 4.7 39.9 1.0
CA B:ASN678 4.7 42.3 1.0
O1B B:TPP2001 4.8 41.0 1.0
C B:ASN678 4.8 45.4 1.0
C B:GLY644 4.8 44.1 1.0
CA B:GLY644 4.9 38.3 1.0

Reference:

T.Wagner, M.Bellinzoni, A.M.Wehenkel, H.M.O'hare, P.M.Alzari. Functional Plasticity and Allosteric Regulation of Alpha-Ketoglutarate Decarboxylase in Central Mycobacterial Metabolism. Chem.Biol. V. 18 1011 2011.
ISSN: ISSN 1074-5521
PubMed: 21867916
DOI: 10.1016/J.CHEMBIOL.2011.06.004
Page generated: Wed Aug 14 07:17:27 2024

Last articles

Zn in 9JYW
Zn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy