Magnesium in PDB 2xzs: Death Associated Protein Kinase 1 Residues 1-312

All present enzymatic activity of Death Associated Protein Kinase 1 Residues 1-312:
2.7.11.1;

The structure of Death Associated Protein Kinase 1 Residues 1-312, PDB code: 2xzs was solved by H.Yumerefendi, P.J.Mas, N.Dordevic, A.A.Mccarthy, D.J.Hart, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	43.36 / 2.00
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	56.300, 49.610, 130.500, 90.00, 94.52, 90.00
R / Rfree (%)	18.255 / 22.471

The binding sites of Magnesium atom in the Death Associated Protein Kinase 1 Residues 1-312 (pdb code 2xzs). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Death Associated Protein Kinase 1 Residues 1-312, PDB code: 2xzs:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Death Associated Protein Kinase 1 Residues 1-312


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Death Associated Protein Kinase 1 Residues 1-312 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1313 b:35.5 occ:1.00 OD2 A:ASP161 2.1 13.4 0.7 O A:HOH2095 2.1 40.8 1.0 OD1 A:ASN144 2.1 12.4 1.0 OD2 A:ASP161 2.5 18.4 0.3 CG A:ASN144 3.1 13.0 1.0 CG A:ASP161 3.1 17.9 0.7 CG A:ASP161 3.3 14.5 0.3 ND2 A:ASN144 3.5 12.3 1.0 CB A:ASP161 3.6 11.7 0.3 CB A:ASP161 3.6 12.3 0.7 O A:HOH2106 3.7 36.5 1.0 OD1 A:ASP161 4.2 14.7 0.7 O A:GLU143 4.3 14.9 1.0 CG A:GLU143 4.3 29.8 1.0 CB A:ASN144 4.4 11.9 1.0 OD1 A:ASP161 4.5 16.0 0.3 CD1 A:ILE160 4.5 13.2 1.0 OE2 A:GLU143 4.5 46.4 1.0 C A:GLU143 4.6 16.9 1.0 CA A:ASN144 4.7 11.8 1.0 N A:ASN144 4.8 12.8 1.0 CD A:GLU143 5.0 44.4 1.0 CG1 A:ILE160 5.0 8.7 1.0

Magnesium binding site 2 out of 2 in the Death Associated Protein Kinase 1 Residues 1-312


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Death Associated Protein Kinase 1 Residues 1-312 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1303 b:63.4 occ:1.00 OD2 B:ASP161 2.4 25.1 0.2 OD2 B:ASP161 2.4 35.2 0.8 OD1 B:ASN144 2.6 28.7 1.0 CG B:ASP161 3.3 31.8 0.8 CG B:ASP161 3.4 26.3 0.2 CG B:ASN144 3.4 28.4 1.0 ND2 B:ASN144 3.4 24.5 1.0 CB B:ASP161 3.6 28.8 0.8 CB B:ASP161 3.7 27.4 0.2 OD2 B:ASP139 4.2 28.6 1.0 OD1 B:ASP161 4.4 36.5 0.8 OD1 B:ASP161 4.5 25.3 0.2 CE B:LYS141 4.7 33.1 1.0 NZ B:LYS141 4.7 38.7 1.0 CB B:ASN144 4.8 28.7 1.0

B.Simon, A.Huart, K.Temmerman, J.Vahokoski, H.D.T.Mertens, D.Komadina, J.Hoffmann, H.Yumerefendi, D.I.Svergun, P.Kursula, C.Schultz, A.A.Mccarthy, D.J.Hart, M.Wilmanns. Death-Associated Protein Kinase Activity Is Regulated By Coupled Calcium/Calmodulin Binding to Two Distinct Sites. Structure V. 24 851 2016.
ISSN: ISSN 0969-2126
PubMed: 27133022
DOI: 10.1016/J.STR.2016.03.020