Magnesium »
PDB 2ybb-2yni »
2ynd »
Magnesium in PDB 2ynd: Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor.
Enzymatic activity of Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor.
All present enzymatic activity of Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor.:
2.3.1.97;
2.3.1.97;
Protein crystallography data
The structure of Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor., PDB code: 2ynd
was solved by
M.H.Wright,
B.Clough,
M.D.Rackham,
J.A.Brannigan,
M.Grainger,
A.R.Bottrill,
W.P.Heal,
M.Broncel,
R.A.Serwa,
D.Mann,
R.J.Leatherbarrow,
A.J.Wilkinson,
A.A.Holder,
E.W.Tate,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
| Resolution Low / High (Å) | 59.60 / 1.89 |
| Space group | P 21 21 21 |
| Cell size a, b, c (Å), α, β, γ (°) | 57.450, 119.050, 176.730, 90.00, 90.00, 90.00 |
| R / Rfree (%) | 16.768 / 22.316 |
Other elements in 2ynd:
The structure of Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor. also contains other interesting chemical elements:
| Chlorine | (Cl) | 9 atoms |
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor.
(pdb code 2ynd). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor., PDB code: 2ynd:
Jump to Magnesium binding site number: 1; 2; 3;
In total 3 binding sites of Magnesium where determined in the Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor., PDB code: 2ynd:
Jump to Magnesium binding site number: 1; 2; 3;
Magnesium binding site 1 out of 3 in 2ynd
Go back to
Magnesium Binding Sites List in 2ynd
Magnesium binding site 1 out
of 3 in the Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 1 of Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor. within 5.0Å range:
|
Magnesium binding site 2 out of 3 in 2ynd
Go back to
Magnesium Binding Sites List in 2ynd
Magnesium binding site 2 out
of 3 in the Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 2 of Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor. within 5.0Å range:
|
Magnesium binding site 3 out of 3 in 2ynd
Go back to
Magnesium Binding Sites List in 2ynd
Magnesium binding site 3 out
of 3 in the Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor.
Mono view
Stereo pair view
Mono view
Stereo pair view
A full contact list of Magnesium with other atoms in the Mg binding
site number 3 of Plasmodium Vivax N-Myristoyltransferase in Complex with A Pyrazole Sulphonamide Inhibitor. within 5.0Å range:
|
Reference:
M.H.Wright,
B.Clough,
M.D.Rackham,
K.Rangachari,
J.A.Brannigan,
M.Grainger,
D.K.Moss,
A.R.Bottrill,
W.P.Heal,
M.Broncel,
R.A.Serwa,
D.Brady,
D.Mann,
R.J.Leatherbarrow,
R.Tewari,
A.J.Wilkinson,
A.A.Holder,
E.W.Tate.
Validation of N-Myristoyltransferase As An Antimalarial Drug Target Using An Integrated Chemical Biology Approach. Nat.Chem. V. 6 112 2014.
ISSN: ISSN 1755-4330
PubMed: 24451586
DOI: 10.1038/NCHEM.1836
Page generated: Wed Aug 14 07:35:49 2024
ISSN: ISSN 1755-4330
PubMed: 24451586
DOI: 10.1038/NCHEM.1836
Last articles
Zn in 9JYWZn in 9IR4
Zn in 9IR3
Zn in 9GMX
Zn in 9GMW
Zn in 9JEJ
Zn in 9ERF
Zn in 9ERE
Zn in 9EGV
Zn in 9EGW
