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Atomistry » Magnesium » PDB 2ybb-2yni » 2yng | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 2ybb-2yni » 2yng » |
Magnesium in PDB 2yng: Hiv-1 Reverse Transcriptase in Complex with Inhibitor GSK560Enzymatic activity of Hiv-1 Reverse Transcriptase in Complex with Inhibitor GSK560
All present enzymatic activity of Hiv-1 Reverse Transcriptase in Complex with Inhibitor GSK560:
2.7.7.49; 2.7.7.7; 3.1.13.2; 3.1.26.13; Protein crystallography data
The structure of Hiv-1 Reverse Transcriptase in Complex with Inhibitor GSK560, PDB code: 2yng
was solved by
P.Chong,
P.Sebahar,
M.Youngman,
D.Garrido,
H.Zhang,
E.L.Stewart,
R.T.Nolte,
L.Wang,
R.G.Ferris,
M.Edelstein,
K.Weaver,
A.Mathis,
A.Peat,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 2yng:
The structure of Hiv-1 Reverse Transcriptase in Complex with Inhibitor GSK560 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Hiv-1 Reverse Transcriptase in Complex with Inhibitor GSK560
(pdb code 2yng). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Hiv-1 Reverse Transcriptase in Complex with Inhibitor GSK560, PDB code: 2yng: Jump to Magnesium binding site number: 1; 2; 3; Magnesium binding site 1 out of 3 in 2yngGo back to Magnesium Binding Sites List in 2yng
Magnesium binding site 1 out
of 3 in the Hiv-1 Reverse Transcriptase in Complex with Inhibitor GSK560
Mono view Stereo pair view
Magnesium binding site 2 out of 3 in 2yngGo back to Magnesium Binding Sites List in 2yng
Magnesium binding site 2 out
of 3 in the Hiv-1 Reverse Transcriptase in Complex with Inhibitor GSK560
Mono view Stereo pair view
Magnesium binding site 3 out of 3 in 2yngGo back to Magnesium Binding Sites List in 2yng
Magnesium binding site 3 out
of 3 in the Hiv-1 Reverse Transcriptase in Complex with Inhibitor GSK560
Mono view Stereo pair view
Reference:
P.Chong,
P.Sebahar,
M.Youngman,
D.Garrido,
H.Zhang,
E.L.Stewart,
R.T.Nolte,
L.Wang,
R.G.Ferris,
M.Edelstein,
K.Weaver,
A.Mathis,
A.Peat.
Rational Design of Potent Non-Nucleoside Inhibitors of Hiv- 1 Reverse Transcriptase. J.Med.Chem. V. 55 10601 2012.
Page generated: Wed Aug 14 07:36:59 2024
ISSN: ISSN 0022-2623 PubMed: 23137340 DOI: 10.1021/JM301294G |
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