Magnesium in PDB 2z7q: Crystal Structure of the N-Terminal Kinase Domain of Human Rsk-1 Bound to Amp-Pcp

All present enzymatic activity of Crystal Structure of the N-Terminal Kinase Domain of Human Rsk-1 Bound to Amp-Pcp:
2.7.11.1;

The structure of Crystal Structure of the N-Terminal Kinase Domain of Human Rsk-1 Bound to Amp-Pcp, PDB code: 2z7q was solved by M.Ikuta, S.K.Munshi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	20.00 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	52.194, 53.685, 119.874, 90.00, 90.00, 90.00
R / Rfree (%)	n/a / n/a

The binding sites of Magnesium atom in the Crystal Structure of the N-Terminal Kinase Domain of Human Rsk-1 Bound to Amp-Pcp (pdb code 2z7q). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the N-Terminal Kinase Domain of Human Rsk-1 Bound to Amp-Pcp, PDB code: 2z7q:

Magnesium binding site 1 out of 1 in the Crystal Structure of the N-Terminal Kinase Domain of Human Rsk-1 Bound to Amp-Pcp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the N-Terminal Kinase Domain of Human Rsk-1 Bound to Amp-Pcp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:66.8 occ:1.00 OD2 A:ASP205 2.2 58.8 1.0 O2B A:ACP500 2.4 60.4 1.0 O1A A:ACP500 2.5 57.9 1.0 OD1 A:ASN192 2.5 39.8 1.0 O2G A:ACP500 2.9 67.3 1.0 CG A:ASP205 3.1 57.2 1.0 CG2 A:THR204 3.6 39.6 1.0 OD1 A:ASP205 3.6 57.2 1.0 PA A:ACP500 3.6 59.1 1.0 PB A:ACP500 3.6 61.5 1.0 CG A:ASN192 3.7 39.3 1.0 O5' A:ACP500 3.9 57.8 1.0 O3A A:ACP500 4.0 60.6 1.0 O A:HOH538 4.1 66.4 1.0 PG A:ACP500 4.3 67.7 1.0 C8 A:ACP500 4.3 49.9 1.0 CB A:ASP205 4.3 54.9 1.0 CA A:ASN192 4.3 36.3 1.0 OG1 A:THR204 4.4 49.8 1.0 O A:GLU191 4.4 38.7 1.0 C3B A:ACP500 4.4 64.8 1.0 CB A:ASN192 4.5 36.5 1.0 CB A:THR204 4.6 46.2 1.0 ND2 A:ASN192 4.7 39.3 1.0 C2' A:ACP500 4.7 52.5 1.0 O1B A:ACP500 4.8 62.2 1.0 O2A A:ACP500 4.9 59.3 1.0 N7 A:ACP500 4.9 48.3 1.0

M.Ikuta, M.Kornienko, N.Byrne, J.C.Reid, S.Mizuarai, H.Kotani, S.K.Munshi. Crystal Structures of the N-Terminal Kinase Domain of Human RSK1 Bound to Three Different Ligands: Implications For the Design of RSK1 Specific Inhibitors. Protein Sci. V. 16 2626 2007.
ISSN: ISSN 0961-8368
PubMed: 17965187
DOI: 10.1110/PS.073123707