Magnesium in PDB 2zxe: Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State

The structure of Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State, PDB code: 2zxe was solved by T.Shinoda, H.Ogawa, F.Cornelius, C.Toyoshima, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	15.00 / 2.40
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	223.815, 50.914, 163.786, 90.00, 105.12, 90.00
R / Rfree (%)	24.6 / 27.1

The structure of Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State also contains other interesting chemical elements:

Fluorine	(F)	4 atoms
Potassium	(K)	3 atoms

The binding sites of Magnesium atom in the Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State (pdb code 2zxe). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State, PDB code: 2zxe:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2001 b:32.4 occ:1.00 MG A:MF42001 0.0 32.4 1.0 F3 A:MF42001 2.0 33.0 1.0 F1 A:MF42001 2.0 31.8 1.0 F4 A:MF42001 2.0 29.8 1.0 F2 A:MF42001 2.0 31.1 1.0 OD2 A:ASP376 2.5 25.3 1.0 OG1 A:THR617 3.3 24.6 1.0 O A:THR219 3.5 28.3 1.0 CG A:ASP376 3.6 26.4 1.0 N A:GLY618 3.8 24.9 1.0 N A:THR378 3.8 25.0 1.0 CB A:THR378 3.8 25.4 1.0 MG A:MG2002 3.9 26.6 1.0 OE1 A:GLU221 3.9 31.4 1.0 OD1 A:ASP376 3.9 25.8 1.0 OG1 A:THR378 4.0 25.7 1.0 O A:HOH5055 4.1 20.4 1.0 CA A:GLY220 4.1 28.0 1.0 CB A:THR617 4.1 24.3 1.0 CA A:THR617 4.3 24.4 1.0 N A:LYS377 4.4 25.7 1.0 O A:GLY220 4.4 28.0 1.0 CA A:THR378 4.4 25.3 1.0 C A:GLY220 4.4 28.2 1.0 ND2 A:ASN720 4.5 28.3 1.0 NZ A:LYS698 4.5 28.1 1.0 C A:THR219 4.5 28.7 1.0 N A:ASP619 4.6 26.4 1.0 C A:THR617 4.6 24.5 1.0 O A:HOH5058 4.6 23.2 1.0 CA A:GLY618 4.6 25.3 1.0 O A:THR378 4.6 25.2 1.0 N A:GLY220 4.8 28.1 1.0 C A:LYS377 4.8 25.2 1.0 CB A:ASP376 4.9 26.2 1.0 CD A:GLU221 4.9 30.7 1.0 CA A:LYS377 5.0 25.3 1.0 C A:GLY618 5.0 25.9 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of the Sodium - Potassium Pump in the E2.2K+.Pi State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg2002 b:26.6 occ:1.00 F2 A:MF42001 1.9 31.1 1.0 O A:THR378 1.9 25.2 1.0 OD2 A:ASP717 1.9 29.9 1.0 OD1 A:ASP376 2.0 25.8 1.0 O A:HOH5058 2.2 23.2 1.0 O A:HOH5055 2.2 20.4 1.0 CG A:ASP717 3.0 29.0 1.0 CG A:ASP376 3.0 26.4 1.0 C A:THR378 3.1 25.6 1.0 OD1 A:ASP717 3.3 31.6 1.0 OD2 A:ASP376 3.4 25.3 1.0 CA A:THR378 3.8 25.3 1.0 MG A:MF42001 3.9 32.4 1.0 N A:THR378 4.0 25.0 1.0 CB A:THR378 4.0 25.4 1.0 N A:GLY379 4.2 25.9 1.0 OG1 A:THR380 4.2 27.0 1.0 OD2 A:ASP721 4.2 31.2 1.0 N A:GLY718 4.2 29.6 1.0 O A:GLY220 4.3 28.0 1.0 CB A:ASP717 4.3 28.9 1.0 CB A:ASP376 4.3 26.2 1.0 N A:ASP717 4.4 28.6 1.0 CA A:GLY379 4.5 26.7 1.0 F4 A:MF42001 4.6 29.8 1.0 F1 A:MF42001 4.6 31.8 1.0 CG2 A:THR378 4.6 23.4 1.0 C A:ASP717 4.7 29.3 1.0 CA A:ASP717 4.7 29.1 1.0 CA A:GLY220 4.7 28.0 1.0 N A:THR380 4.7 27.0 1.0 C A:LYS377 4.8 25.2 1.0 CA A:GLY718 4.8 30.2 1.0 C A:GLY379 4.8 27.2 1.0 C A:GLY220 5.0 28.2 1.0

T.Shinoda, H.Ogawa, F.Cornelius, C.Toyoshima. Crystal Structure of the Sodium - Potassium Pump at 2.4 A Resolution Nature V. 459 446 2009.
ISSN: ISSN 0028-0836
PubMed: 19458722
DOI: 10.1038/NATURE07939