Magnesium in PDB 3c7n: Structure of the HSP110:HSC70 Nucleotide Exchange Complex

The structure of Structure of the HSP110:HSC70 Nucleotide Exchange Complex, PDB code: 3c7n was solved by J.P.Schuermann, J.Jiang, P.J.Hart, R.Sousa, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	42.38 / 3.12
Space group	P 21 21 2
Cell size a, b, c (Å), α, β, γ (°)	123.533, 169.501, 87.724, 90.00, 90.00, 90.00
R / Rfree (%)	22.4 / 28.3

The structure of Structure of the HSP110:HSC70 Nucleotide Exchange Complex also contains other interesting chemical elements:

Fluorine	(F)	3 atoms
Chlorine	(Cl)	3 atoms

The binding sites of Magnesium atom in the Structure of the HSP110:HSC70 Nucleotide Exchange Complex (pdb code 3c7n). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Structure of the HSP110:HSC70 Nucleotide Exchange Complex, PDB code: 3c7n:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Structure of the HSP110:HSC70 Nucleotide Exchange Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the HSP110:HSC70 Nucleotide Exchange Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg667 b:14.8 occ:1.00 O1B A:ADP672 2.2 44.2 1.0 F3 A:BEF671 2.8 39.6 1.0 NZ A:LYS69 3.3 29.6 1.0 PB A:ADP672 3.5 44.2 1.0 N A:ASN11 3.8 30.6 1.0 N A:SER207 3.9 34.0 1.0 BE A:BEF671 3.9 39.6 1.0 N A:HIS206 3.9 23.7 1.0 OG A:SER207 3.9 34.8 1.0 O2B A:ADP672 3.9 44.2 1.0 N A:SER208 4.0 29.2 1.0 CB A:ASN11 4.0 31.1 1.0 CE A:LYS69 4.3 29.2 1.0 CB A:SER208 4.3 29.1 1.0 OG A:SER208 4.3 29.4 1.0 F2 A:BEF671 4.5 39.6 1.0 O3B A:ADP672 4.5 44.2 1.0 CA A:GLY205 4.6 32.2 1.0 CA A:SER207 4.6 34.2 1.0 O3A A:ADP672 4.6 44.2 1.0 CA A:ASN11 4.6 30.7 1.0 CB A:SER207 4.6 33.9 1.0 C A:GLY205 4.6 32.0 1.0 CA A:GLY10 4.6 36.7 1.0 CA A:SER208 4.7 29.1 1.0 CA A:HIS206 4.7 23.7 1.0 C A:SER207 4.7 34.4 1.0 C A:GLY10 4.7 36.9 1.0 CB A:HIS206 4.8 23.7 1.0 C A:HIS206 4.8 24.0 1.0 O A:SER208 4.8 29.2 1.0 CD A:LYS69 4.9 29.6 1.0

Magnesium binding site 2 out of 2 in the Structure of the HSP110:HSC70 Nucleotide Exchange Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the HSP110:HSC70 Nucleotide Exchange Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg558 b:27.8 occ:1.00 OG1 B:THR13 3.2 40.8 1.0 NZ B:LYS71 3.2 47.7 1.0 CG2 B:THR204 3.5 50.1 1.0 N B:THR13 4.2 40.4 1.0 OE2 B:GLU175 4.2 30.0 1.0 OG1 B:THR204 4.4 50.8 1.0 CB B:THR204 4.4 50.4 1.0 CB B:THR13 4.5 40.6 1.0 CE B:LYS71 4.5 49.0 1.0 CA B:GLY12 4.7 37.1 1.0 OE1 B:GLU175 4.9 30.3 1.0 CD B:LYS71 4.9 49.6 1.0 CD B:GLU175 5.0 30.9 1.0 CA B:THR13 5.0 40.6 1.0

J.P.Schuermann, J.Jiang, J.Cuellar, O.Llorca, L.Wang, L.E.Gimenez, S.Jin, A.B.Taylor, B.Demeler, K.A.Morano, P.J.Hart, J.M.Valpuesta, E.M.Lafer, R.Sousa. Structure of the HSP110:HSC70 Nucleotide Exchange Machine Mol.Cell V. 31 232 2008.
ISSN: ISSN 1097-2765
PubMed: 18550409
DOI: 10.1016/J.MOLCEL.2008.05.006