Magnesium in PDB 3cc6: Crystal Structure of Kinase Domain of Protein Tyrosine Kinase 2 Beta (PTK2B)

All present enzymatic activity of Crystal Structure of Kinase Domain of Protein Tyrosine Kinase 2 Beta (PTK2B):
2.7.10.2;

The structure of Crystal Structure of Kinase Domain of Protein Tyrosine Kinase 2 Beta (PTK2B), PDB code: 3cc6 was solved by R.D.Busam, L.Lehtio, T.Karlberg, C.H.Arrowsmith, C.Bountra, R.Collins, L.G.Dahlgren, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, T.Helleday, M.D.Herman, A.Johansson, I.Johansson, A.Kallas, T.Kotenyova, M.Moche, M.E.Nilsson, P.Nordlund, T.Nyman, C.Persson, J.Sagemark, L.Svensson, A.G.Thorsell, L.Tresaugues, S.Van Den Berg, J.Weigelt, M.Welin, H.Berglund, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	18.84 / 1.60
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	37.450, 96.140, 43.200, 90.00, 93.66, 90.00
R / Rfree (%)	18.4 / 21.9

The binding sites of Magnesium atom in the Crystal Structure of Kinase Domain of Protein Tyrosine Kinase 2 Beta (PTK2B) (pdb code 3cc6). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Kinase Domain of Protein Tyrosine Kinase 2 Beta (PTK2B), PDB code: 3cc6:

Magnesium binding site 1 out of 1 in the Crystal Structure of Kinase Domain of Protein Tyrosine Kinase 2 Beta (PTK2B)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Kinase Domain of Protein Tyrosine Kinase 2 Beta (PTK2B) within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg701 b:38.8 occ:1.00 O A:HOH252 1.9 31.6 1.0 O A:HOH121 2.0 28.4 1.0 O A:HOH80 2.0 31.5 1.0 O A:HOH167 2.2 32.2 1.0 OD2 A:ASP668 2.2 25.8 1.0 O A:HOH263 2.4 40.8 1.0 CG A:ASP668 3.4 23.6 1.0 OD1 A:ASP663 3.9 16.4 1.0 OD2 A:ASP663 3.9 17.3 1.0 OD1 A:ASP668 4.1 24.9 1.0 CB A:ASP665 4.3 19.5 1.0 CB A:ASP668 4.3 21.0 1.0 CG A:ASP663 4.3 15.9 1.0 OD2 A:ASP665 4.4 22.4 1.0 O A:HOH165 4.7 41.1 1.0 CG A:ASP665 4.8 20.7 1.0

R.D.Busam, L.Lehtio, T.Karlberg, C.H.Arrowsmith, C.Bountra, R.Collins, L.G.Dahlgren, A.M.Edwards, S.Flodin, A.Flores, S.Graslund, M.Hammarstrom, T.Helleday, M.D.Herman, A.Johansson, I.Johansson, A.Kallas, T.Kotenyova, M.Moche, M.E.Nilsson, P.Nordlund, T.Nyman, C.Persson, J.Sagemark, L.Svensson, A.G.Thorsell, L.Tresaugues, S.Van Den Berg, J.Weigelt, M.Welin, H.Berglund. Structure of Protein Tyrosine Kinase 2 Beta (PTK2B) Kinase Domain. To Be Published.