Magnesium in PDB 3cly: Crystal Structure of Fgf Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction

All present enzymatic activity of Crystal Structure of Fgf Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction:
2.7.10.1;

The structure of Crystal Structure of Fgf Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction, PDB code: 3cly was solved by H.Chen, M.Mohammadi, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 2.00
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	55.437, 68.462, 85.711, 90.00, 90.00, 90.00
R / Rfree (%)	21.6 / 24.7

The binding sites of Magnesium atom in the Crystal Structure of Fgf Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction (pdb code 3cly). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Fgf Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction, PDB code: 3cly:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Fgf Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Fgf Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1801 b:25.6 occ:1.00 OD1 A:ASN1631 2.2 18.2 1.0 OD2 A:ASP1644 2.2 21.4 1.0 O A:HOH1902 2.3 12.7 1.0 O2A A:ACP1803 2.3 24.1 1.0 O A:HOH1901 2.4 27.4 1.0 O1G A:ACP1803 2.4 33.0 1.0 CG A:ASN1631 3.2 18.4 1.0 CG A:ASP1644 3.3 19.4 1.0 PA A:ACP1803 3.4 23.7 1.0 O3A A:ACP1803 3.4 27.4 1.0 PG A:ACP1803 3.5 34.6 1.0 O2G A:ACP1803 3.6 33.4 1.0 CB A:ASP1644 3.7 18.7 1.0 ND2 A:ASN1631 3.7 18.1 1.0 O2B A:ACP1803 3.9 32.6 1.0 PB A:ACP1803 4.0 31.9 1.0 C3B A:ACP1803 4.2 33.0 1.0 O A:HOH1986 4.3 26.6 1.0 O5' A:ACP1803 4.3 23.2 1.0 OD1 A:ASP1644 4.4 19.1 1.0 O1A A:ACP1803 4.4 25.0 1.0 C5' A:ACP1803 4.5 21.4 1.0 CB A:ASN1631 4.5 16.8 1.0 O A:ARG1630 4.6 18.7 1.0 OD1 A:ASP1626 4.6 19.2 1.0 O3G A:ACP1803 4.7 32.9 1.0 CD A:ARG1630 4.7 24.6 1.0 O A:HOH1985 4.7 43.8 1.0 CA A:ASN1631 4.8 17.4 1.0 NE A:ARG1630 4.9 25.8 1.0 CG A:ARG1630 4.9 22.8 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Fgf Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Fgf Receptor 2 (FGFR2) Kinase Domains Trapped in Trans-Phosphorylation Reaction within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1802 b:58.5 occ:1.00 O2B A:ACP1803 2.6 32.6 1.0 OD1 A:ASP1644 3.1 19.1 1.0 O2G A:ACP1803 3.1 33.4 1.0 CA A:GLY1646 3.4 19.9 1.0 OE1 A:GLU1534 3.4 30.5 1.0 O A:HOH1976 3.4 34.4 1.0 PB A:ACP1803 3.8 31.9 1.0 CG A:ASP1644 3.9 19.4 1.0 OD2 A:ASP1644 3.9 21.4 1.0 C3B A:ACP1803 4.0 33.0 1.0 N A:GLY1646 4.1 19.7 1.0 NZ A:LYS1517 4.1 24.5 1.0 PG A:ACP1803 4.3 34.6 1.0 CD A:GLU1534 4.3 30.0 1.0 O1B A:ACP1803 4.4 32.5 1.0 C A:GLY1646 4.4 20.0 1.0 OE2 A:GLU1534 4.8 30.1 1.0 O A:GLY1646 4.8 20.9 1.0

H.Chen, C.F.Xu, J.Ma, A.V.Eliseenkova, W.Li, P.M.Pollock, N.Pitteloud, W.T.Miller, T.A.Neubert, M.Mohammadi. A Crystallographic Snapshot of Tyrosine Trans-Phosphorylation in Action Proc.Natl.Acad.Sci.Usa V. 105 19660 2008.
ISSN: ISSN 0027-8424
PubMed: 19060208
DOI: 10.1073/PNAS.0807752105