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Atomistry » Magnesium » PDB 3cpw-3d19 » 3cu8 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 3cpw-3d19 » 3cu8 » |
Magnesium in PDB 3cu8: Impaired Binding of 14-3-3 to RAF1 Is Linked to Noonan and Leopard SyndromeEnzymatic activity of Impaired Binding of 14-3-3 to RAF1 Is Linked to Noonan and Leopard Syndrome
All present enzymatic activity of Impaired Binding of 14-3-3 to RAF1 Is Linked to Noonan and Leopard Syndrome:
2.7.11.1; Protein crystallography data
The structure of Impaired Binding of 14-3-3 to RAF1 Is Linked to Noonan and Leopard Syndrome, PDB code: 3cu8
was solved by
B.Schumacher,
M.Weyand,
J.Kuhlmann,
C.Ottmann,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Impaired Binding of 14-3-3 to RAF1 Is Linked to Noonan and Leopard Syndrome
(pdb code 3cu8). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Impaired Binding of 14-3-3 to RAF1 Is Linked to Noonan and Leopard Syndrome, PDB code: 3cu8: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 3cu8Go back to Magnesium Binding Sites List in 3cu8
Magnesium binding site 1 out
of 2 in the Impaired Binding of 14-3-3 to RAF1 Is Linked to Noonan and Leopard Syndrome
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 3cu8Go back to Magnesium Binding Sites List in 3cu8
Magnesium binding site 2 out
of 2 in the Impaired Binding of 14-3-3 to RAF1 Is Linked to Noonan and Leopard Syndrome
Mono view Stereo pair view
Reference:
M.Molzan,
B.Schumacher,
C.Ottmann,
A.Baljuls,
L.Polzien,
M.Weyand,
P.Thiel,
R.Rose,
M.Rose,
P.Kuhenne,
M.Kaiser,
U.R.Rapp,
J.Kuhlmann,
C.Ottmann.
Impaired Binding of 14-3-3 to C-Raf in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling. Mol. Cell. Biol. V. 30 4698 2010.
Page generated: Wed Aug 14 11:53:02 2024
ISSN: ESSN 1098-5549 PubMed: 20679480 DOI: 10.1128/MCB.01636-09 |
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