Magnesium in PDB 3dlz: Crystal Structure of Human Haspin in Complex with Amp

All present enzymatic activity of Crystal Structure of Human Haspin in Complex with Amp:
2.7.11.1;

The structure of Crystal Structure of Human Haspin in Complex with Amp, PDB code: 3dlz was solved by P.Filippakopoulos, J.Eswaran, T.Keates, N.Burgess-Brown, J.W.Murray, F.Vondelft, C.H.Arrowsmith, A.M.Edwards, M.Wickstroem, C.Bountra, S.Knapp, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	41.17 / 1.85
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	73.315, 49.729, 98.009, 90.00, 90.00, 90.00
R / Rfree (%)	16.4 / 21.6

The binding sites of Magnesium atom in the Crystal Structure of Human Haspin in Complex with Amp (pdb code 3dlz). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Human Haspin in Complex with Amp, PDB code: 3dlz:

Magnesium binding site 1 out of 1 in the Crystal Structure of Human Haspin in Complex with Amp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Haspin in Complex with Amp within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg901 b:24.6 occ:1.00 OH A:TYR747 2.5 12.6 1.0 OE1 A:GLN718 2.9 19.6 1.0 OD2 A:ASP716 3.0 28.3 1.0 CZ A:TYR747 3.4 12.3 1.0 OD1 A:ASP716 3.4 20.2 1.0 CG A:ASP716 3.4 22.0 1.0 CE1 A:TYR747 3.5 13.9 1.0 CB A:GLN718 3.6 16.2 1.0 CD1 A:TRP652 3.7 15.9 1.0 NE1 A:TRP652 3.7 17.5 1.0 CE A:LYS751 3.7 14.6 1.0 O A:HOH1178 3.7 29.6 1.0 CD A:GLN718 3.8 16.8 1.0 O A:HOH1069 4.0 41.0 1.0 C2 A:EDO903 4.0 49.0 1.0 CG A:GLN718 4.1 16.2 1.0 C1 A:EDO903 4.2 48.6 1.0 NZ A:LYS751 4.3 15.1 1.0 CB A:HIS651 4.3 11.9 1.0 O1 A:EDO903 4.5 49.2 1.0 O A:HOH1028 4.5 29.9 1.0 CB A:ASP716 4.6 20.8 1.0 CE2 A:TYR747 4.6 12.9 1.0 CG A:TRP652 4.7 13.7 1.0 CE2 A:TRP652 4.7 15.3 1.0 O A:HOH1266 4.7 46.7 1.0 CA A:GLN718 4.8 15.9 1.0 N A:TRP652 4.8 13.9 1.0 CD1 A:TYR747 4.9 13.9 1.0 N A:GLN718 4.9 15.8 1.0 NE2 A:GLN718 5.0 18.1 1.0

J.Eswaran, D.Patnaik, P.Filippakopoulos, F.Wang, R.L.Stein, J.W.Murray, J.M.Higgins, S.Knapp. Structure and Functional Characterization of the Atypical Human Kinase Haspin. Proc.Natl.Acad.Sci.Usa V. 106 20198 2009.
ISSN: ISSN 0027-8424
PubMed: 19918057
DOI: 10.1073/PNAS.0901989106