Atomistry » Magnesium » PDB 3fzn-3g8c » 3g2f
Atomistry »
  Magnesium »
    PDB 3fzn-3g8c »
      3g2f »

Magnesium in PDB 3g2f: Crystal Structure of the Kinase Domain of Bone Morphogenetic Protein Receptor Type II (BMPR2) at 2.35 A Resolution

Enzymatic activity of Crystal Structure of the Kinase Domain of Bone Morphogenetic Protein Receptor Type II (BMPR2) at 2.35 A Resolution

All present enzymatic activity of Crystal Structure of the Kinase Domain of Bone Morphogenetic Protein Receptor Type II (BMPR2) at 2.35 A Resolution:
2.7.11.30;

Protein crystallography data

The structure of Crystal Structure of the Kinase Domain of Bone Morphogenetic Protein Receptor Type II (BMPR2) at 2.35 A Resolution, PDB code: 3g2f was solved by A.Chaikuad, C.Thangaratnarajah, A.K.Roos, P.Filippakopoulos, E.Salah, C.Phillips, T.Keates, O.Fedorov, R.Chalk, K.Petrie, A.C.W.Pike, F.Vondelft, C.H.Arrowsmith, A.M.Edwards, J.Weigelt, C.Bountra, S.Knapp, A.Bullock, Structural Genomics Consortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 47.35 / 2.35
Space group P 21 21 2
Cell size a, b, c (Å), α, β, γ (°) 94.540, 218.793, 44.187, 90.00, 90.00, 90.00
R / Rfree (%) 20.8 / 24.6

Other elements in 3g2f:

The structure of Crystal Structure of the Kinase Domain of Bone Morphogenetic Protein Receptor Type II (BMPR2) at 2.35 A Resolution also contains other interesting chemical elements:

Arsenic (As) 5 atoms

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of the Kinase Domain of Bone Morphogenetic Protein Receptor Type II (BMPR2) at 2.35 A Resolution (pdb code 3g2f). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of the Kinase Domain of Bone Morphogenetic Protein Receptor Type II (BMPR2) at 2.35 A Resolution, PDB code: 3g2f:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in 3g2f

Go back to Magnesium Binding Sites List in 3g2f
Magnesium binding site 1 out of 2 in the Crystal Structure of the Kinase Domain of Bone Morphogenetic Protein Receptor Type II (BMPR2) at 2.35 A Resolution


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Kinase Domain of Bone Morphogenetic Protein Receptor Type II (BMPR2) at 2.35 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg901

b:40.5
occ:1.00
 OD2 A:ASP351 1.9 15.8 1.0
O A:HOH119 2.0 23.1 1.0
O A:HOH76 2.1 18.7 1.0
O2A A:ADP900 2.1 42.4 1.0
O2B A:ADP900 2.1 50.0 1.0
OD1 A:ASN338 2.2 19.8 1.0
CG A:ASP351 3.0 17.5 1.0
PB A:ADP900 3.1 49.8 1.0
PA A:ADP900 3.3 40.8 1.0
CG A:ASN338 3.3 21.1 1.0
O3B A:ADP900 3.3 46.9 1.0
O3A A:ADP900 3.5 42.8 1.0
CB A:ASP351 3.7 17.8 1.0
ND2 A:ASN338 3.7 22.6 1.0
OD1 A:ASP351 4.1 14.1 1.0
O A:HOH77 4.2 31.4 1.0
O1A A:ADP900 4.3 41.8 1.0
O A:HOH62 4.3 25.4 1.0
O5' A:ADP900 4.4 38.4 1.0
O1B A:ADP900 4.4 51.1 1.0
C5' A:ADP900 4.5 35.8 1.0
CB A:ASN338 4.6 19.8 1.0
O A:ARG337 4.7 19.8 1.0
CA A:ASN338 4.8 20.7 1.0
C A:ARG337 4.9 19.5 1.0
O3' A:ADP900 4.9 32.9 1.0

Magnesium binding site 2 out of 2 in 3g2f

Go back to Magnesium Binding Sites List in 3g2f
Magnesium binding site 2 out of 2 in the Crystal Structure of the Kinase Domain of Bone Morphogenetic Protein Receptor Type II (BMPR2) at 2.35 A Resolution


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of the Kinase Domain of Bone Morphogenetic Protein Receptor Type II (BMPR2) at 2.35 A Resolution within 5.0Å range:
probe atom residue distance (Å) B Occ
B:Mg901

b:47.2
occ:1.00
 O2B B:ADP900 2.0 63.5 1.0
OD2 B:ASP351 2.0 17.6 1.0
O2A B:ADP900 2.1 56.5 1.0
OD1 B:ASN338 2.2 18.3 1.0
PB B:ADP900 3.2 61.1 1.0
CG B:ASN338 3.2 15.7 1.0
CG B:ASP351 3.2 21.1 1.0
PA B:ADP900 3.4 53.9 1.0
O3B B:ADP900 3.5 60.6 1.0
ND2 B:ASN338 3.6 15.0 1.0
O3A B:ADP900 3.7 55.9 1.0
CB B:ASP351 3.8 21.6 1.0
OD1 B:ASP351 4.2 20.8 1.0
C5' B:ADP900 4.3 48.0 1.0
O5' B:ADP900 4.4 50.9 1.0
O1B B:ADP900 4.4 62.7 1.0
CB B:ASN338 4.5 16.1 1.0
O B:ARG337 4.6 15.9 1.0
O1A B:ADP900 4.6 54.6 1.0
CA B:GLY212 4.6 23.2 1.0
CA B:ASN338 4.8 16.0 1.0
C B:ARG337 4.8 16.0 1.0
N B:ARG213 4.8 24.0 1.0
N B:ASN338 4.9 16.4 1.0
O3' B:ADP900 4.9 46.5 1.0

Reference:

A.Chaikuad, C.Thangaratnarajah, F.Von Delft, A.N.Bullock. Structural Consequences of BMPR2 Kinase Domain Mutations Causing Pulmonary Arterial Hypertension. Sci Rep V. 9 18351 2019.
ISSN: ESSN 2045-2322
PubMed: 31797984
DOI: 10.1038/S41598-019-54830-7
Page generated: Mon Dec 14 08:09:48 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy