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Atomistry » Magnesium » PDB 3fzn-3g8c » 3g3n » |
Magnesium in PDB 3g3n: PDE7A Catalytic Domain in Complex with 3-(2,6- Difluorophenyl)-2-(Methylthio)Quinazolin-4(3H)-OneEnzymatic activity of PDE7A Catalytic Domain in Complex with 3-(2,6- Difluorophenyl)-2-(Methylthio)Quinazolin-4(3H)-One
All present enzymatic activity of PDE7A Catalytic Domain in Complex with 3-(2,6- Difluorophenyl)-2-(Methylthio)Quinazolin-4(3H)-One:
3.1.4.17; Protein crystallography data
The structure of PDE7A Catalytic Domain in Complex with 3-(2,6- Difluorophenyl)-2-(Methylthio)Quinazolin-4(3H)-One, PDB code: 3g3n
was solved by
T.Castano,
H.Wang,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3g3n:
The structure of PDE7A Catalytic Domain in Complex with 3-(2,6- Difluorophenyl)-2-(Methylthio)Quinazolin-4(3H)-One also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the PDE7A Catalytic Domain in Complex with 3-(2,6- Difluorophenyl)-2-(Methylthio)Quinazolin-4(3H)-One
(pdb code 3g3n). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the PDE7A Catalytic Domain in Complex with 3-(2,6- Difluorophenyl)-2-(Methylthio)Quinazolin-4(3H)-One, PDB code: 3g3n: Magnesium binding site 1 out of 1 in 3g3nGo back to Magnesium Binding Sites List in 3g3n
Magnesium binding site 1 out
of 1 in the PDE7A Catalytic Domain in Complex with 3-(2,6- Difluorophenyl)-2-(Methylthio)Quinazolin-4(3H)-One
Mono view Stereo pair view
Reference:
T.Castano,
H.Wang,
N.E.Campillo,
S.Ballester,
C.Gonzalez-Garcia,
J.Hernandez,
C.Perez,
J.Cuenca,
A.Perez-Castillo,
A.Martinez,
O.Huertas,
J.L.Gelpi,
F.J.Luque,
H.Ke,
C.Gil.
Synthesis, Structural Analysis, and Biological Evaluation of Thioxoquinazoline Derivatives As Phosphodiesterase 7 Inhibitors Chemmedchem V. 4 866 2009.
Page generated: Wed Aug 14 14:02:11 2024
ISSN: ISSN 1860-7179 PubMed: 19350606 DOI: 10.1002/CMDC.200900043 |
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