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Atomistry » Magnesium » PDB 3gnz-3gx2 » 3gol | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 3gnz-3gx2 » 3gol » |
Magnesium in PDB 3gol: Hcv NS5B Polymerase in Complex with 1,5 Benzodiazepine Inhibitor (R)- 11DEnzymatic activity of Hcv NS5B Polymerase in Complex with 1,5 Benzodiazepine Inhibitor (R)- 11D
All present enzymatic activity of Hcv NS5B Polymerase in Complex with 1,5 Benzodiazepine Inhibitor (R)- 11D:
2.7.7.48; Protein crystallography data
The structure of Hcv NS5B Polymerase in Complex with 1,5 Benzodiazepine Inhibitor (R)- 11D, PDB code: 3gol
was solved by
O.Nyanguile,
H.De Bondt,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3gol:
The structure of Hcv NS5B Polymerase in Complex with 1,5 Benzodiazepine Inhibitor (R)- 11D also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Hcv NS5B Polymerase in Complex with 1,5 Benzodiazepine Inhibitor (R)- 11D
(pdb code 3gol). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Hcv NS5B Polymerase in Complex with 1,5 Benzodiazepine Inhibitor (R)- 11D, PDB code: 3gol: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 3golGo back to![]() ![]()
Magnesium binding site 1 out
of 2 in the Hcv NS5B Polymerase in Complex with 1,5 Benzodiazepine Inhibitor (R)- 11D
![]() Mono view ![]() Stereo pair view
Magnesium binding site 2 out of 2 in 3golGo back to![]() ![]()
Magnesium binding site 2 out
of 2 in the Hcv NS5B Polymerase in Complex with 1,5 Benzodiazepine Inhibitor (R)- 11D
![]() Mono view ![]() Stereo pair view
Reference:
D.Mcgowan,
O.Nyanguile,
M.D.Cummings,
S.Vendeville,
K.Vandyck,
W.Van Den Broeck,
C.W.Boutton,
H.De Bondt,
L.Quirynen,
K.Amssoms,
J.F.Bonfanti,
S.Last,
K.Rombauts,
A.Tahri,
L.Hu,
F.Delouvroy,
K.Vermeiren,
G.Vandercruyssen,
L.Van Der Helm,
E.Cleiren,
W.Mostmans,
P.Lory,
G.Pille,
K.Van Emelen,
G.Fanning,
F.Pauwels,
T.I.Lin,
K.Simmen,
P.Raboisson.
1,5-Benzodiazepine Inhibitors of Hcv NS5B Polymerase. Bioorg.Med.Chem.Lett. V. 19 2492 2009.
Page generated: Mon Dec 14 08:11:58 2020
ISSN: ISSN 0960-894X PubMed: 19342234 DOI: 10.1016/J.BMCL.2009.03.035 |
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