Magnesium in PDB 3gpc: Crystal Structure of Human Acyl-Coa Synthetase Medium-Chain Family Member 2A (L64P Mutation) in A Complex with Coa

All present enzymatic activity of Crystal Structure of Human Acyl-Coa Synthetase Medium-Chain Family Member 2A (L64P Mutation) in A Complex with Coa:
6.2.1.2;

The structure of Crystal Structure of Human Acyl-Coa Synthetase Medium-Chain Family Member 2A (L64P Mutation) in A Complex with Coa, PDB code: 3gpc was solved by E.S.Pilka, G.T.Kochan, W.W.Yue, C.Bhatia, F.Von Delft, C.H.Arrowsmith, A.M.Edwards, J.Weigelt, C.Bountra, U.Oppermann, Structural Genomicsconsortium (Sgc), with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	50.00 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	55.604, 97.535, 118.210, 90.00, 89.99, 90.00
R / Rfree (%)	16.2 / 22.6

The binding sites of Magnesium atom in the Crystal Structure of Human Acyl-Coa Synthetase Medium-Chain Family Member 2A (L64P Mutation) in A Complex with Coa (pdb code 3gpc). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human Acyl-Coa Synthetase Medium-Chain Family Member 2A (L64P Mutation) in A Complex with Coa, PDB code: 3gpc:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Human Acyl-Coa Synthetase Medium-Chain Family Member 2A (L64P Mutation) in A Complex with Coa


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Acyl-Coa Synthetase Medium-Chain Family Member 2A (L64P Mutation) in A Complex with Coa within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg901 b:44.5 occ:1.00 O A:VAL488 2.7 24.9 1.0 O A:HOH957 2.8 28.5 1.0 O A:MET483 2.8 27.9 1.0 O A:HIS485 2.9 18.6 1.0 C A:HIS485 3.7 23.2 1.0 C A:VAL488 3.8 20.6 1.0 C A:MET483 4.0 27.5 1.0 CA A:PRO486 4.0 24.9 1.0 N A:PRO486 4.2 24.8 1.0 O A:PRO486 4.2 20.3 1.0 C A:PRO486 4.3 22.7 1.0 N A:VAL488 4.4 21.3 1.0 CA A:VAL488 4.5 18.0 1.0 C A:GLU484 4.5 33.1 1.0 N A:HIS485 4.6 28.8 1.0 CA A:MET483 4.7 25.7 1.0 O A:GLU484 4.7 38.7 1.0 CB A:VAL488 4.7 17.8 1.0 CA A:HIS485 4.8 26.0 1.0 N A:VAL489 4.9 17.8 1.0 N A:GLU484 4.9 29.8 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Human Acyl-Coa Synthetase Medium-Chain Family Member 2A (L64P Mutation) in A Complex with Coa


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human Acyl-Coa Synthetase Medium-Chain Family Member 2A (L64P Mutation) in A Complex with Coa within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg901 b:35.3 occ:1.00 O B:MET483 2.7 29.4 1.0 O B:VAL488 2.9 18.9 1.0 O B:HIS485 3.0 20.4 1.0 O B:HOH611 3.0 46.6 1.0 C B:MET483 3.7 26.6 1.0 C B:HIS485 3.8 23.5 1.0 CA B:PRO486 4.0 19.4 1.0 C B:VAL488 4.0 18.6 1.0 N B:PRO486 4.3 20.6 1.0 CA B:MET483 4.4 23.1 1.0 C B:PRO486 4.4 18.6 1.0 N B:HIS485 4.4 24.3 1.0 C B:GLU484 4.5 29.1 1.0 N B:VAL488 4.5 19.7 1.0 O B:PRO486 4.5 22.3 1.0 CA B:VAL488 4.6 17.3 1.0 N B:GLU484 4.7 26.3 1.0 CB B:VAL488 4.7 19.6 1.0 CA B:HIS485 4.8 23.8 1.0 CA B:GLU484 4.8 28.7 1.0 O B:GLU484 4.9 32.2 1.0

G.Kochan, E.S.Pilka, F.Von Delft, U.Oppermann, W.W.Yue. Structural Snapshots For the Conformation-Dependent Catalysis By Human Medium-Chain Acyl-Coenzyme A Synthetase ACSM2A J.Mol.Biol. V. 388 997 2009.
ISSN: ISSN 0022-2836
PubMed: 19345228
DOI: 10.1016/J.JMB.2009.03.064