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Atomistry » Magnesium » PDB 3hd2-3hoz » 3hdz » |
Magnesium in PDB 3hdz: Identification, Synthesis, and Sar of Amino Substituted Pyrido[3, 2B]Pryaziones As Potent and Selective PDE5 InhibitorsEnzymatic activity of Identification, Synthesis, and Sar of Amino Substituted Pyrido[3, 2B]Pryaziones As Potent and Selective PDE5 Inhibitors
All present enzymatic activity of Identification, Synthesis, and Sar of Amino Substituted Pyrido[3, 2B]Pryaziones As Potent and Selective PDE5 Inhibitors:
3.1.4.35; 3.1.4.53; Protein crystallography data
The structure of Identification, Synthesis, and Sar of Amino Substituted Pyrido[3, 2B]Pryaziones As Potent and Selective PDE5 Inhibitors, PDB code: 3hdz
was solved by
J.W.Cubbage,
D.G.Brown,
E.J.Jacobsen,
J.K.Walker,
R.O.Hughes,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3hdz:
The structure of Identification, Synthesis, and Sar of Amino Substituted Pyrido[3, 2B]Pryaziones As Potent and Selective PDE5 Inhibitors also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Identification, Synthesis, and Sar of Amino Substituted Pyrido[3, 2B]Pryaziones As Potent and Selective PDE5 Inhibitors
(pdb code 3hdz). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Identification, Synthesis, and Sar of Amino Substituted Pyrido[3, 2B]Pryaziones As Potent and Selective PDE5 Inhibitors, PDB code: 3hdz: Magnesium binding site 1 out of 1 in 3hdzGo back to Magnesium Binding Sites List in 3hdz
Magnesium binding site 1 out
of 1 in the Identification, Synthesis, and Sar of Amino Substituted Pyrido[3, 2B]Pryaziones As Potent and Selective PDE5 Inhibitors
Mono view Stereo pair view
Reference:
D.R.Owen,
J.K.Walker,
E.Jon Jacobsen,
J.N.Freskos,
R.O.Hughes,
D.L.Brown,
A.S.Bell,
D.G.Brown,
C.Phillips,
B.V.Mischke,
J.M.Molyneaux,
Y.M.Fobian,
S.E.Heasley,
J.B.Moon,
W.C.Stallings,
D.Joseph Rogier,
D.N.Fox,
M.J.Palmer,
T.Ringer,
M.Rodriquez-Lens,
J.W.Cubbage,
R.M.Blevis-Bal,
A.G.Benson,
B.A.Acker,
T.M.Maddux,
M.B.Tollefson,
B.R.Bond,
A.Macinnes,
Y.Yu.
Identification, Synthesis and Sar of Amino Substituted Pyrido[3,2B]Pyrazinones As Potent and Selective PDE5 Inhibitors. Bioorg.Med.Chem.Lett. 2009.
Page generated: Mon Dec 14 08:13:28 2020
ISSN: ESSN 1464-3405 PubMed: 19540112 DOI: 10.1016/J.BMCL.2009.06.012 |
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