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Atomistry » Magnesium » PDB 3hp6-3hwx » 3hqz | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 3hp6-3hwx » 3hqz » |
Magnesium in PDB 3hqz: Discovery of Novel Inhibitors of PDE10AEnzymatic activity of Discovery of Novel Inhibitors of PDE10AProtein crystallography data
The structure of Discovery of Novel Inhibitors of PDE10A, PDB code: 3hqz
was solved by
J.Pandit,
E.S.Marr,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3hqz:
The structure of Discovery of Novel Inhibitors of PDE10A also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Discovery of Novel Inhibitors of PDE10A
(pdb code 3hqz). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Discovery of Novel Inhibitors of PDE10A, PDB code: 3hqz: Magnesium binding site 1 out of 1 in 3hqzGo back to![]() ![]()
Magnesium binding site 1 out
of 1 in the Discovery of Novel Inhibitors of PDE10A
![]() Mono view ![]() Stereo pair view
Reference:
P.R.Verhoest,
D.S.Chapin,
M.Corman,
K.Fonseca,
J.F.Harms,
X.Hou,
E.S.Marr,
F.S.Menniti,
F.Nelson,
R.O'connor,
J.Pandit,
C.Proulx-Lafrance,
A.W.Schmidt,
C.J.Schmidt,
J.A.Suiciak,
S.Liras.
Discovery of A Novel Class of Phosphodiesterase 10A Inhibitors and Identification of Clinical Candidate 2-[4-(1-Methyl-4-Pyridin-4-Yl-1H-Pyrazol-3-Yl)- Phenoxymethyl]-Quinoline (Pf-2545920) For the Treatment of Schizophrenia J.Med.Chem. V. 52 5188 2009.
Page generated: Wed Aug 14 15:18:34 2024
ISSN: ISSN 0022-2623 PubMed: 19630403 DOI: 10.1021/JM900521K |
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