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Magnesium in PDB 3jwr: Crystal Structure of Chimeric PDE5/PDE6 Catalytic Domain Complexed with 3-Isobutyl-1-Methylxanthine (Ibmx) and PDE6 Gamma-Subunit Inhibitory Peptide 70-87.Enzymatic activity of Crystal Structure of Chimeric PDE5/PDE6 Catalytic Domain Complexed with 3-Isobutyl-1-Methylxanthine (Ibmx) and PDE6 Gamma-Subunit Inhibitory Peptide 70-87.
All present enzymatic activity of Crystal Structure of Chimeric PDE5/PDE6 Catalytic Domain Complexed with 3-Isobutyl-1-Methylxanthine (Ibmx) and PDE6 Gamma-Subunit Inhibitory Peptide 70-87.:
3.1.4.17; 3.1.4.35; Protein crystallography data
The structure of Crystal Structure of Chimeric PDE5/PDE6 Catalytic Domain Complexed with 3-Isobutyl-1-Methylxanthine (Ibmx) and PDE6 Gamma-Subunit Inhibitory Peptide 70-87., PDB code: 3jwr
was solved by
B.Barren,
L.Gakhar,
H.Muradov,
K.K.Boyd,
S.Ramaswamy,
N.O.Artemyev,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3jwr:
The structure of Crystal Structure of Chimeric PDE5/PDE6 Catalytic Domain Complexed with 3-Isobutyl-1-Methylxanthine (Ibmx) and PDE6 Gamma-Subunit Inhibitory Peptide 70-87. also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Crystal Structure of Chimeric PDE5/PDE6 Catalytic Domain Complexed with 3-Isobutyl-1-Methylxanthine (Ibmx) and PDE6 Gamma-Subunit Inhibitory Peptide 70-87.
(pdb code 3jwr). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Chimeric PDE5/PDE6 Catalytic Domain Complexed with 3-Isobutyl-1-Methylxanthine (Ibmx) and PDE6 Gamma-Subunit Inhibitory Peptide 70-87., PDB code: 3jwr: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 3jwrGo back to Magnesium Binding Sites List in 3jwr
Magnesium binding site 1 out
of 2 in the Crystal Structure of Chimeric PDE5/PDE6 Catalytic Domain Complexed with 3-Isobutyl-1-Methylxanthine (Ibmx) and PDE6 Gamma-Subunit Inhibitory Peptide 70-87.
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 3jwrGo back to Magnesium Binding Sites List in 3jwr
Magnesium binding site 2 out
of 2 in the Crystal Structure of Chimeric PDE5/PDE6 Catalytic Domain Complexed with 3-Isobutyl-1-Methylxanthine (Ibmx) and PDE6 Gamma-Subunit Inhibitory Peptide 70-87.
Mono view Stereo pair view
Reference:
B.Barren,
L.Gakhar,
H.Muradov,
K.K.Boyd,
S.Ramaswamy,
N.O.Artemyev.
Structural Basis of Phosphodiesterase 6 Inhibition By the C-Terminal Region of the Gamma-Subunit Embo J. V. 28 3613 2009.
Page generated: Mon Dec 14 08:20:53 2020
ISSN: ISSN 0261-4189 PubMed: 19798052 DOI: 10.1038/EMBOJ.2009.284 |
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