Magnesium in PDB 3ken: Human EG5 in Complex with S-Trityl-L-Cysteine

The structure of Human EG5 in Complex with S-Trityl-L-Cysteine, PDB code: 3ken was solved by C.L.Parke, E.J.Wojcik, S.Kim, D.K.Worthylake, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.00 / 2.50
Space group	I 21 3
Cell size a, b, c (Å), α, β, γ (°)	157.930, 157.930, 157.930, 90.00, 90.00, 90.00
R / Rfree (%)	24.1 / 27.5

The binding sites of Magnesium atom in the Human EG5 in Complex with S-Trityl-L-Cysteine (pdb code 3ken). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human EG5 in Complex with S-Trityl-L-Cysteine, PDB code: 3ken:

Magnesium binding site 1 out of 1 in the Human EG5 in Complex with S-Trityl-L-Cysteine


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Human EG5 in Complex with S-Trityl-L-Cysteine within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg701 b:14.2 occ:1.00 O A:HOH428 2.2 6.1 1.0 O A:HOH387 2.3 3.1 1.0 O A:HOH392 2.3 13.6 1.0 O1B A:ADP1452 2.3 23.8 1.0 OG1 A:THR112 2.3 8.2 1.0 O A:HOH393 2.4 34.5 1.0 PB A:ADP1452 3.4 20.1 1.0 CB A:THR112 3.4 10.6 1.0 O3B A:ADP1452 3.5 20.8 1.0 O A:HOH410 4.0 16.9 1.0 O2A A:ADP1452 4.0 30.1 1.0 O A:SER232 4.1 17.5 1.0 OD2 A:ASP265 4.1 14.0 1.0 O A:HOH388 4.1 15.1 1.0 N A:THR112 4.2 10.3 1.0 OG A:SER232 4.2 27.5 1.0 O2B A:ADP1452 4.4 24.4 1.0 CA A:THR112 4.4 10.4 1.0 O A:HOH411 4.4 35.0 1.0 OD1 A:ASP265 4.5 13.3 1.0 CG2 A:THR112 4.5 8.2 1.0 O1A A:ADP1452 4.6 20.0 1.0 PA A:ADP1452 4.6 24.9 1.0 O3A A:ADP1452 4.6 25.5 1.0 CG A:ASP265 4.7 15.4 1.0 O A:HOH400 4.9 15.9 1.0 NZ A:LYS111 4.9 3.9 1.0 CE A:LYS111 4.9 6.8 1.0 C A:SER232 4.9 20.1 1.0 O A:HOH377 4.9 24.3 1.0

E.D.Kim, R.Buckley, S.Learman, J.Richard, C.Parke, D.K.Worthylake, E.J.Wojcik, R.A.Walker, S.Kim. Allosteric Drug Discrimination Is Coupled to Mechanochemical Changes in the Kinesin-5 Motor Core. J.Biol.Chem. V. 285 18650 2010.
ISSN: ISSN 0021-9258
PubMed: 20299460
DOI: 10.1074/JBC.M109.092072