Magnesium in PDB 3kjv: Hiv-1 Reverse Transcriptase in Complex with Dna

All present enzymatic activity of Hiv-1 Reverse Transcriptase in Complex with Dna:
2.7.7.49;

The structure of Hiv-1 Reverse Transcriptase in Complex with Dna, PDB code: 3kjv was solved by E.B.Lansdon, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.84 / 3.10
Space group	C 2 2 21
Cell size a, b, c (Å), α, β, γ (°)	165.423, 171.973, 103.398, 90.00, 90.00, 90.00
R / Rfree (%)	25.7 / 32.9

The binding sites of Magnesium atom in the Hiv-1 Reverse Transcriptase in Complex with Dna (pdb code 3kjv). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Hiv-1 Reverse Transcriptase in Complex with Dna, PDB code: 3kjv:

Magnesium binding site 1 out of 1 in the Hiv-1 Reverse Transcriptase in Complex with Dna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Hiv-1 Reverse Transcriptase in Complex with Dna within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg601 b:1.8 occ:1.00 OD2 A:ASP498 2.2 28.7 1.0 OE1 A:GLU478 2.4 39.2 1.0 OD1 A:ASP443 2.5 32.1 1.0 OD1 A:ASP498 2.6 30.0 1.0 CG A:ASP498 2.7 29.8 1.0 OD2 A:ASP443 2.9 35.6 1.0 OE2 A:GLU478 2.9 41.5 1.0 CG A:ASP443 2.9 33.2 1.0 CD A:GLU478 3.0 41.6 1.0 O A:GLY444 3.7 38.1 1.0 CB A:ASP498 4.0 27.8 1.0 CB A:ASP443 4.3 32.0 1.0 N A:GLY444 4.4 32.7 1.0 CG A:GLU478 4.4 41.5 1.0 OP1 T:DC723 4.4 58.2 1.0 CA A:ASP443 4.6 31.4 1.0 C A:GLY444 4.7 38.3 1.0 OD2 A:ASP549 4.7 62.0 1.0 C A:ASP443 4.9 31.5 1.0

E.B.Lansdon, D.Samuel, L.Lagpacan, K.M.Brendza, K.L.White, M.Hung, X.Liu, C.G.Boojamra, R.L.Mackman, T.Cihlar, A.S.Ray, M.E.Mcgrath, S.Swaminathan. Visualizing the Molecular Interactions of A Nucleotide Analog, Gs-9148, with Hiv-1 Reverse Transcriptase-Dna Complex. J.Mol.Biol. V. 397 967 2010.
ISSN: ISSN 0022-2836
PubMed: 20156454
DOI: 10.1016/J.JMB.2010.02.019