Atomistry » Magnesium » PDB 3kk2-3ktq » 3klh
Atomistry »
  Magnesium »
    PDB 3kk2-3ktq »
      3klh »

Magnesium in PDB 3klh: Crystal Structure of Azt-Resistant Hiv-1 Reverse Transcriptase Crosslinked to Post-Translocation Aztmp-Terminated Dna (Complex P)

Enzymatic activity of Crystal Structure of Azt-Resistant Hiv-1 Reverse Transcriptase Crosslinked to Post-Translocation Aztmp-Terminated Dna (Complex P)

All present enzymatic activity of Crystal Structure of Azt-Resistant Hiv-1 Reverse Transcriptase Crosslinked to Post-Translocation Aztmp-Terminated Dna (Complex P):
2.7.7.49; 2.7.7.7; 3.1.26.4;

Protein crystallography data

The structure of Crystal Structure of Azt-Resistant Hiv-1 Reverse Transcriptase Crosslinked to Post-Translocation Aztmp-Terminated Dna (Complex P), PDB code: 3klh was solved by X.Tu, S.G.Sarafianos, E.Arnold, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 24.79 / 2.90
Space group P 32 1 2
Cell size a, b, c (Å), α, β, γ (°) 166.472, 166.472, 220.822, 90.00, 90.00, 120.00
R / Rfree (%) 26 / 29.4

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of Azt-Resistant Hiv-1 Reverse Transcriptase Crosslinked to Post-Translocation Aztmp-Terminated Dna (Complex P) (pdb code 3klh). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Azt-Resistant Hiv-1 Reverse Transcriptase Crosslinked to Post-Translocation Aztmp-Terminated Dna (Complex P), PDB code: 3klh:

Magnesium binding site 1 out of 1 in 3klh

Go back to Magnesium Binding Sites List in 3klh
Magnesium binding site 1 out of 1 in the Crystal Structure of Azt-Resistant Hiv-1 Reverse Transcriptase Crosslinked to Post-Translocation Aztmp-Terminated Dna (Complex P)


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Azt-Resistant Hiv-1 Reverse Transcriptase Crosslinked to Post-Translocation Aztmp-Terminated Dna (Complex P) within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg1001

b:29.0
occ:1.00
OD2 A:ASP498 2.2 44.1 1.0
OE1 A:GLU478 2.4 45.9 1.0
OD1 A:ASP443 2.6 74.8 1.0
OE2 A:GLU478 2.7 49.8 1.0
CD A:GLU478 3.0 49.0 1.0
CG A:ASP498 3.3 50.0 1.0
CG A:ASP443 3.5 73.8 1.0
OD1 A:ASP498 3.7 49.1 1.0
OD2 A:ASP443 3.7 73.4 1.0
O A:GLY444 3.9 74.5 1.0
NE2 A:HIS539 3.9 78.4 1.0
CB A:ALA538 4.2 65.0 1.0
CD2 A:HIS539 4.4 78.2 1.0
CG A:GLU478 4.5 50.2 1.0
OP1 E:DC723 4.6 1.0 1.0
CB A:ASP498 4.6 51.0 1.0
N A:GLY444 4.9 73.8 1.0
CB A:ASP443 5.0 72.1 1.0
OD1 A:ASP549 5.0 87.9 1.0

Reference:

X.Tu, K.Das, Q.Han, J.D.Bauman, A.D.Clark, X.Hou, Y.V.Frenkel, B.L.Gaffney, R.A.Jones, P.L.Boyer, S.H.Hughes, S.G.Sarafianos, E.Arnold. Structural Basis of Hiv-1 Resistance to Azt By Excision. Nat.Struct.Mol.Biol. V. 17 1202 2010.
ISSN: ISSN 1545-9993
PubMed: 20852643
DOI: 10.1038/NSMB.1908
Page generated: Mon Dec 14 08:22:47 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy