Magnesium in PDB 3ksl: Structure of Fpt Bound to Datfp-Dh-Gpp

All present enzymatic activity of Structure of Fpt Bound to Datfp-Dh-Gpp:
2.5.1.58;

The structure of Structure of Fpt Bound to Datfp-Dh-Gpp, PDB code: 3ksl was solved by M.L.Hovlid, R.L.Edelstein, O.Henry, J.Ochocki, A.Degraw, S.Lenevich, T.Talbot, V.Young, A.W.Hruza, F.Lopez-Gallego, N.P.Labello, C.L.Strickland, C.Schmidt-Dannert, M.D.Distefano, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	29.45 / 2.05
Space group	P 61
Cell size a, b, c (Å), α, β, γ (°)	171.191, 171.191, 69.217, 90.00, 90.00, 120.00
R / Rfree (%)	18 / 21.4

The structure of Structure of Fpt Bound to Datfp-Dh-Gpp also contains other interesting chemical elements:

Fluorine	(F)	6 atoms
Zinc	(Zn)	1 atom

The binding sites of Magnesium atom in the Structure of Fpt Bound to Datfp-Dh-Gpp (pdb code 3ksl). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structure of Fpt Bound to Datfp-Dh-Gpp, PDB code: 3ksl:

Magnesium binding site 1 out of 1 in the Structure of Fpt Bound to Datfp-Dh-Gpp


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of Fpt Bound to Datfp-Dh-Gpp within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1001 b:32.3 occ:1.00 O A:HOH582 2.2 29.4 1.0 NE2 B:HIS194 2.3 37.1 1.0 O A:HOH583 2.4 26.4 1.0 O B:HOH638 2.8 69.1 1.0 CE1 B:HIS194 3.2 36.9 1.0 CD2 B:HIS194 3.3 37.4 1.0 CB A:TYR131 4.0 23.3 1.0 CG A:GLN167 4.1 28.9 1.0 NE2 A:GLN167 4.4 49.4 1.0 ND1 B:HIS194 4.4 37.8 1.0 CG B:HIS194 4.4 35.8 1.0 O B:HOH651 4.5 47.8 1.0 CD2 A:HIS170 4.5 25.8 1.0 O A:HOH387 4.5 23.2 1.0 CA B:GLY197 4.7 43.8 1.0 NE2 B:HIS149 4.7 28.1 1.0 CD A:GLN167 4.8 49.1 1.0 CG A:TYR131 4.9 26.0 1.0 CG A:HIS170 4.9 24.5 1.0 CD2 B:HIS149 5.0 28.6 1.0 CB A:GLN167 5.0 23.7 1.0

M.L.Hovlid, R.L.Edelstein, O.Henry, J.Ochocki, A.Degraw, S.Lenevich, T.Talbot, V.G.Young, A.W.Hruza, F.Lopez-Gallego, N.P.Labello, C.L.Strickland, C.Schmidt-Dannert, M.D.Distefano. Synthesis, Properties, and Applications of Diazotrifluropropanoyl-Containing Photoactive Analogs of Farnesyl Diphosphate Containing Modified Linkages For Enhanced Stability. Chem.Biol.Drug Des. V. 75 51 2010.
ISSN: ISSN 1747-0277
PubMed: 19954434
DOI: 10.1111/J.1747-0285.2009.00914.X