Magnesium in PDB 3mwe: Truncated Human Atp-Citrate Lyase with Tartrate Bound

All present enzymatic activity of Truncated Human Atp-Citrate Lyase with Tartrate Bound:
2.3.3.8;

The structure of Truncated Human Atp-Citrate Lyase with Tartrate Bound, PDB code: 3mwe was solved by M.E.Fraser, T.Sun, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.74 / 2.20
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	168.191, 60.793, 109.176, 90.00, 124.96, 90.00
R / Rfree (%)	17.9 / 22.8

The binding sites of Magnesium atom in the Truncated Human Atp-Citrate Lyase with Tartrate Bound (pdb code 3mwe). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Truncated Human Atp-Citrate Lyase with Tartrate Bound, PDB code: 3mwe:

Magnesium binding site 1 out of 1 in the Truncated Human Atp-Citrate Lyase with Tartrate Bound


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Truncated Human Atp-Citrate Lyase with Tartrate Bound within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg426 b:48.6 occ:1.00 O A:HOH624 2.5 45.6 1.0 O A:ASP257 2.6 38.3 1.0 O A:ALA262 2.6 43.0 1.0 O A:SER260 2.7 39.9 1.0 OD1 A:ASP257 2.8 33.6 1.0 C A:ASP257 3.5 40.1 1.0 CG A:ASP257 3.6 31.4 1.0 C A:SER260 3.7 48.2 1.0 C A:ALA262 3.7 38.3 1.0 OG A:SER260 3.7 41.7 0.6 CA A:ASP257 4.1 35.9 1.0 C A:GLY261 4.1 45.6 1.0 OD2 A:ASP257 4.2 40.4 1.0 O A:GLY261 4.2 48.4 1.0 CA A:SER263 4.3 33.4 1.0 N A:ALA262 4.4 42.5 1.0 CB A:ASP257 4.4 31.9 1.0 N A:SER263 4.4 33.8 1.0 CA A:SER260 4.5 48.0 0.6 N A:GLY261 4.5 49.5 1.0 N A:SER260 4.5 50.3 1.0 CA A:GLY261 4.5 45.0 1.0 CA A:SER260 4.6 47.9 0.5 N A:ALA258 4.6 41.2 1.0 CB A:SER260 4.6 48.0 0.6 CA A:ALA262 4.7 37.0 1.0 N A:LEU264 4.9 34.1 1.0 CA A:ALA258 4.9 43.9 1.0 CB A:SER260 4.9 48.0 0.5

T.Sun, K.Hayakawa, K.S.Bateman, M.E.Fraser. Identification of the Citrate-Binding Site of Human Atp-Citrate Lyase Using X-Ray Crystallography. J.Biol.Chem. V. 285 27418 2010.
ISSN: ISSN 0021-9258
PubMed: 20558738
DOI: 10.1074/JBC.M109.078667