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Atomistry » Magnesium » PDB 3r11-3ren » 3r21 » |
Magnesium in PDB 3r21: Design, Synthesis, and Biological Evaluation of Pyrazolopyridine- Sulfonamides As Potent Multiple-Mitotic Kinase (Mmk) Inhibitors (Part I)Enzymatic activity of Design, Synthesis, and Biological Evaluation of Pyrazolopyridine- Sulfonamides As Potent Multiple-Mitotic Kinase (Mmk) Inhibitors (Part I)
All present enzymatic activity of Design, Synthesis, and Biological Evaluation of Pyrazolopyridine- Sulfonamides As Potent Multiple-Mitotic Kinase (Mmk) Inhibitors (Part I):
2.7.11.1; Protein crystallography data
The structure of Design, Synthesis, and Biological Evaluation of Pyrazolopyridine- Sulfonamides As Potent Multiple-Mitotic Kinase (Mmk) Inhibitors (Part I), PDB code: 3r21
was solved by
L.Zhang,
J.Fan,
J.-H.Chong,
A.Cesena,
B.Tam,
C.Gilson,
C.Boykin,
D.Wang,
D.Marcotte,
J.-Y.Le Brazidec,
D.Aivazian,
J.Piao,
K.Lundgren,
K.Hong,
K.Vu,
K.Nguyen,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Design, Synthesis, and Biological Evaluation of Pyrazolopyridine- Sulfonamides As Potent Multiple-Mitotic Kinase (Mmk) Inhibitors (Part I)
(pdb code 3r21). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Design, Synthesis, and Biological Evaluation of Pyrazolopyridine- Sulfonamides As Potent Multiple-Mitotic Kinase (Mmk) Inhibitors (Part I), PDB code: 3r21: Magnesium binding site 1 out of 1 in 3r21Go back to Magnesium Binding Sites List in 3r21
Magnesium binding site 1 out
of 1 in the Design, Synthesis, and Biological Evaluation of Pyrazolopyridine- Sulfonamides As Potent Multiple-Mitotic Kinase (Mmk) Inhibitors (Part I)
Mono view Stereo pair view
Reference:
L.Zhang,
J.Fan,
J.H.Chong,
A.Cesena,
B.Y.Tam,
C.Gilson,
C.Boykin,
D.Wang,
D.Aivazian,
D.Marcotte,
G.Xiao,
J.Y.Le Brazidec,
J.Piao,
K.Lundgren,
K.Hong,
K.Vu,
K.Nguyen,
L.S.Gan,
L.Silvian,
L.Ling,
M.Teng,
M.Reff,
N.Takeda,
N.Timple,
Q.Wang,
R.Morena,
S.Khan,
S.Zhao,
T.Li,
W.C.Lee,
A.G.Taveras,
J.Chao.
Design, Synthesis, and Biological Evaluation of Pyrazolopyrimidine-Sulfonamides As Potent Multiple-Mitotic Kinase (Mmk) Inhibitors (Part I). Bioorg.Med.Chem.Lett. V. 21 5633 2011.
Page generated: Mon Dec 14 08:43:55 2020
ISSN: ISSN 0960-894X PubMed: 21798738 DOI: 10.1016/J.BMCL.2011.06.129 |
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