Magnesium in PDB 3s5f: Crystal Structure of Human Frataxin Variant W155F

All present enzymatic activity of Crystal Structure of Human Frataxin Variant W155F:
1.16.3.1;

The structure of Crystal Structure of Human Frataxin Variant W155F, PDB code: 3s5f was solved by C.-L.Tsai, J.Bridwell-Rabb, D.P.Barondeau, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.85 / 1.50
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	47.680, 53.120, 48.480, 90.00, 112.30, 90.00
R / Rfree (%)	16.4 / 21.3

The binding sites of Magnesium atom in the Crystal Structure of Human Frataxin Variant W155F (pdb code 3s5f). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure of Human Frataxin Variant W155F, PDB code: 3s5f:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure of Human Frataxin Variant W155F


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Human Frataxin Variant W155F within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1034 b:40.5 occ:1.00 OG1 A:THR119 2.3 22.2 1.0 O A:LYS116 2.3 17.6 1.0 O A:ALA114 2.4 18.1 1.0 O A:HOH1098 2.6 27.1 1.0 O A:THR119 3.2 22.0 1.0 C A:ALA114 3.4 16.8 1.0 CB A:THR119 3.5 18.1 1.0 C A:LYS116 3.5 17.2 1.0 C A:THR119 3.8 19.5 1.0 CA A:THR119 3.9 18.2 1.0 N A:THR119 3.9 17.5 1.0 N A:LYS116 3.9 15.2 1.0 CA A:ALA114 4.0 17.1 1.0 O A:LEU113 4.1 18.4 1.0 C A:ASP115 4.4 16.5 1.0 CA A:LYS116 4.4 17.6 1.0 N A:ASP115 4.4 16.1 1.0 CA A:PRO117 4.4 17.8 1.0 N A:PRO117 4.5 16.6 1.0 C A:PRO117 4.6 17.4 1.0 O A:PHE120 4.7 17.9 1.0 CA A:ASP115 4.7 18.1 1.0 CG2 A:THR119 4.7 15.3 1.0 O A:PRO117 4.9 19.6 1.0 N A:TYR118 5.0 16.8 1.0 O A:ASP115 5.0 19.0 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure of Human Frataxin Variant W155F


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure of Human Frataxin Variant W155F within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1132 b:23.3 occ:1.00 O B:HOH1095 2.2 28.2 1.0 O B:LYS116 2.2 20.7 1.0 OG1 B:THR119 2.3 16.8 1.0 O B:HOH1071 2.5 29.1 1.0 O B:THR119 2.6 20.0 1.0 O B:ALA114 2.6 20.9 1.0 C B:LYS116 3.4 20.8 1.0 C B:THR119 3.4 17.0 1.0 CB B:THR119 3.5 15.7 1.0 C B:ALA114 3.6 20.0 1.0 CA B:THR119 3.7 16.7 1.0 N B:LYS116 3.8 22.6 1.0 N B:THR119 3.9 17.2 1.0 O B:LEU113 4.1 17.4 1.0 O B:PHE120 4.1 17.5 1.0 CA B:LYS116 4.2 21.5 1.0 C B:ASP115 4.2 24.3 1.0 CA B:ALA114 4.4 19.2 1.0 N B:PRO117 4.4 20.8 1.0 N B:ASP115 4.4 22.5 1.0 O B:HOH1080 4.5 32.8 1.0 CA B:PRO117 4.6 21.7 1.0 N B:PHE120 4.6 17.3 1.0 CA B:ASP115 4.6 25.5 1.0 C B:PHE120 4.7 17.7 1.0 O B:ASP115 4.7 24.8 1.0 C B:PRO117 4.7 21.0 1.0 CG2 B:THR119 4.8 16.0 1.0 CB B:LYS116 4.9 21.7 1.0 N B:TYR118 4.9 18.9 1.0

C.L.Tsai, J.Bridwell-Rabb, D.P.Barondeau. Friedreich'S Ataxia Variants I154F and W155R Diminish Frataxin-Based Activation of the Iron-Sulfur Cluster Assembly Complex. Biochemistry V. 50 6478 2011.
ISSN: ISSN 0006-2960
PubMed: 21671584
DOI: 10.1021/BI200666H