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Atomistry » Magnesium » PDB 3tar-3tm0 » 3tgg » |
Magnesium in PDB 3tgg: A Novel Series of Potent and Selective PDE5 INHIBITOR2Enzymatic activity of A Novel Series of Potent and Selective PDE5 INHIBITOR2
All present enzymatic activity of A Novel Series of Potent and Selective PDE5 INHIBITOR2:
3.1.4.35; Protein crystallography data
The structure of A Novel Series of Potent and Selective PDE5 INHIBITOR2, PDB code: 3tgg
was solved by
S.Han,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3tgg:
The structure of A Novel Series of Potent and Selective PDE5 INHIBITOR2 also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the A Novel Series of Potent and Selective PDE5 INHIBITOR2
(pdb code 3tgg). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the A Novel Series of Potent and Selective PDE5 INHIBITOR2, PDB code: 3tgg: Magnesium binding site 1 out of 1 in 3tggGo back to Magnesium Binding Sites List in 3tgg
Magnesium binding site 1 out
of 1 in the A Novel Series of Potent and Selective PDE5 INHIBITOR2
Mono view Stereo pair view
Reference:
R.O.Hughes,
T.Maddux,
D.Joseph Rogier,
S.Lu,
J.K.Walker,
E.Jon Jacobsen,
J.M.Rumsey,
Y.Zheng,
A.Macinnes,
B.R.Bond,
S.Han.
Investigation of the Pyrazinones As PDE5 Inhibitors: Evaluation of Regioisomeric Projections Into the Solvent Region. Bioorg.Med.Chem.Lett. V. 21 6348 2011.
Page generated: Mon Dec 14 08:54:19 2020
ISSN: ISSN 0960-894X PubMed: 21955943 DOI: 10.1016/J.BMCL.2011.08.106 |
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