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Atomistry » Magnesium » PDB 3u8u-3umo » 3ui7 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 3u8u-3umo » 3ui7 » |
Magnesium in PDB 3ui7: Discovery of Orally Active Pyrazoloquinoline As A Potent PDE10 Inhibitor For the Management of SchizophreniaEnzymatic activity of Discovery of Orally Active Pyrazoloquinoline As A Potent PDE10 Inhibitor For the Management of Schizophrenia
All present enzymatic activity of Discovery of Orally Active Pyrazoloquinoline As A Potent PDE10 Inhibitor For the Management of Schizophrenia:
3.1.4.17; 3.1.4.35; Protein crystallography data
The structure of Discovery of Orally Active Pyrazoloquinoline As A Potent PDE10 Inhibitor For the Management of Schizophrenia, PDB code: 3ui7
was solved by
S.Yang,
J.Smotryski,
W.Mcelroy,
G.Ho,
D.Tulshian,
W.J.Greenlee,
R.Hodgson,
L.Xiao,
A.Hruza,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 3ui7:
The structure of Discovery of Orally Active Pyrazoloquinoline As A Potent PDE10 Inhibitor For the Management of Schizophrenia also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Discovery of Orally Active Pyrazoloquinoline As A Potent PDE10 Inhibitor For the Management of Schizophrenia
(pdb code 3ui7). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Discovery of Orally Active Pyrazoloquinoline As A Potent PDE10 Inhibitor For the Management of Schizophrenia, PDB code: 3ui7: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 3ui7Go back to Magnesium Binding Sites List in 3ui7
Magnesium binding site 1 out
of 2 in the Discovery of Orally Active Pyrazoloquinoline As A Potent PDE10 Inhibitor For the Management of Schizophrenia
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 3ui7Go back to Magnesium Binding Sites List in 3ui7
Magnesium binding site 2 out
of 2 in the Discovery of Orally Active Pyrazoloquinoline As A Potent PDE10 Inhibitor For the Management of Schizophrenia
Mono view Stereo pair view
Reference:
S.W.Yang,
J.Smotryski,
W.T.Mcelroy,
Z.Tan,
G.Ho,
D.Tulshian,
W.J.Greenlee,
M.Guzzi,
X.Zhang,
D.Mullins,
L.Xiao,
A.Hruza,
T.M.Chan,
D.Rindgen,
C.Bleickardt,
R.Hodgson.
Discovery of Orally Active Pyrazoloquinolines As Potent PDE10 Inhibitors For the Management of Schizophrenia. Bioorg.Med.Chem.Lett. V. 22 235 2012.
Page generated: Thu Aug 15 12:30:57 2024
ISSN: ISSN 0960-894X PubMed: 22142545 DOI: 10.1016/J.BMCL.2011.11.023 |
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