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Atomistry » Magnesium » PDB 3zi8-3zwk » 3zjt | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 3zi8-3zwk » 3zjt » |
Magnesium in PDB 3zjt: Ternary Complex of E .Coli Leucyl-Trna Synthetase, Trna(Leu) 574 the Benzoxaborole AN3017 in the Editing ConformationEnzymatic activity of Ternary Complex of E .Coli Leucyl-Trna Synthetase, Trna(Leu) 574 the Benzoxaborole AN3017 in the Editing Conformation
All present enzymatic activity of Ternary Complex of E .Coli Leucyl-Trna Synthetase, Trna(Leu) 574 the Benzoxaborole AN3017 in the Editing Conformation:
6.1.1.4; Protein crystallography data
The structure of Ternary Complex of E .Coli Leucyl-Trna Synthetase, Trna(Leu) 574 the Benzoxaborole AN3017 in the Editing Conformation, PDB code: 3zjt
was solved by
S.Cusack,
A.Palencia,
T.Crepin,
V.Hernandez,
T.Akama,
S.J.Baker,
W.Bu,
L.Feng,
Y.R.Freund,
L.Liu,
M.Meewan,
M.Mohan,
W.Mao,
F.L.Rock,
H.Sexton,
A.Sheoran,
Y.Zhang,
Y.Zhang,
Y.Zhou,
J.A.Nieman,
M.R.Anugula,
E.M.Keramane,
K.Savariraj,
D.S.Reddy,
R.Sharma,
R.Subedi,
R.Singh,
A.Oleary,
N.L.Simon,
P.L.Demarsh,
S.Mushtaq,
M.Warner,
D.M.Livermore,
M.R.K.Alley,
J.J.Plattner,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Ternary Complex of E .Coli Leucyl-Trna Synthetase, Trna(Leu) 574 the Benzoxaborole AN3017 in the Editing Conformation
(pdb code 3zjt). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 3 binding sites of Magnesium where determined in the Ternary Complex of E .Coli Leucyl-Trna Synthetase, Trna(Leu) 574 the Benzoxaborole AN3017 in the Editing Conformation, PDB code: 3zjt: Jump to Magnesium binding site number: 1; 2; 3; Magnesium binding site 1 out of 3 in 3zjtGo back to Magnesium Binding Sites List in 3zjt
Magnesium binding site 1 out
of 3 in the Ternary Complex of E .Coli Leucyl-Trna Synthetase, Trna(Leu) 574 the Benzoxaborole AN3017 in the Editing Conformation
Mono view Stereo pair view
Magnesium binding site 2 out of 3 in 3zjtGo back to Magnesium Binding Sites List in 3zjt
Magnesium binding site 2 out
of 3 in the Ternary Complex of E .Coli Leucyl-Trna Synthetase, Trna(Leu) 574 the Benzoxaborole AN3017 in the Editing Conformation
Mono view Stereo pair view
Magnesium binding site 3 out of 3 in 3zjtGo back to Magnesium Binding Sites List in 3zjt
Magnesium binding site 3 out
of 3 in the Ternary Complex of E .Coli Leucyl-Trna Synthetase, Trna(Leu) 574 the Benzoxaborole AN3017 in the Editing Conformation
Mono view Stereo pair view
Reference:
V.Hernandez,
T.Crepin,
A.Palencia,
S.Cusack,
T.Akama,
S.J.Baker,
W.Bu,
L.Feng,
Y.R.Freund,
L.Liu,
M.Meewan,
M.Mohan,
W.Mao,
F.L.Rock,
H.Sexton,
A.Sheoran,
Y.Zhang,
Y.Zhang,
Y.Zhou,
J.A.Nieman,
M.R.Anugula,
E.M.Keramane,
K.Savariraj,
D.S.Reddy,
R.Sharma,
R.Subedi,
R.Singh,
A.O'leary,
N.L.Simon,
P.L.De Marsh,
S.Mushtaq,
M.Warner,
D.M.Livermore,
M.R.K.Alley,
J.J.Plattner.
Discovery of A Novel Class of Boron-Based Antibacterials with Activity Against Gram-Negative Bacteria. Antimicrob.Agents Chemother. V. 57 1394 2013.
Page generated: Mon Dec 14 09:03:42 2020
ISSN: ISSN 0066-4804 PubMed: 23295920 DOI: 10.1128/AAC.02058-12 |
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