Magnesium in PDB 470d: Crystal Structure and Improved Antisense Properties of 2'-O-(2- Methoxyethyl)-Rna

The structure of Crystal Structure and Improved Antisense Properties of 2'-O-(2- Methoxyethyl)-Rna, PDB code: 470d was solved by M.Teplova, G.Minasov, V.Tereshko, G.Inamati, P.D.Cook, M.Egli, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	8.00 / 1.95
Space group	C 1 2 1
Cell size a, b, c (Å), α, β, γ (°)	42.000, 35.600, 47.140, 90.00, 93.20, 90.00
R / Rfree (%)	20.9 / 25.7

The binding sites of Magnesium atom in the Crystal Structure and Improved Antisense Properties of 2'-O-(2- Methoxyethyl)-Rna (pdb code 470d). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Crystal Structure and Improved Antisense Properties of 2'-O-(2- Methoxyethyl)-Rna, PDB code: 470d:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Crystal Structure and Improved Antisense Properties of 2'-O-(2- Methoxyethyl)-Rna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure and Improved Antisense Properties of 2'-O-(2- Methoxyethyl)-Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg100 b:28.0 occ:1.00 O B:HOH103 1.9 32.2 1.0 O A:HOH101 2.0 32.1 1.0 O B:HOH104 2.1 39.0 1.0 O B:HOH102 2.1 21.5 1.0 O A:HOH105 2.4 38.2 1.0 OP1 B:C4315 4.2 21.6 1.0 OP2 A:C433 4.2 22.6 1.0 O B:HOH150 4.2 27.1 1.0 OP1 B:G4816 4.2 17.1 1.0 OP2 B:G4816 4.3 17.8 1.0 O A:HOH128 4.3 36.6 1.0 OP1 A:G482 4.3 29.4 1.0 OP1 A:C433 4.4 24.8 1.0 O A:HOH171 4.5 33.7 1.0 P B:G4816 4.7 20.2 1.0 P A:C433 4.8 18.6 1.0

Magnesium binding site 2 out of 2 in the Crystal Structure and Improved Antisense Properties of 2'-O-(2- Methoxyethyl)-Rna


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Crystal Structure and Improved Antisense Properties of 2'-O-(2- Methoxyethyl)-Rna within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg106 b:20.2 occ:0.50 O A:HOH107 2.0 14.8 1.0 O A:HOH109 2.0 23.7 1.0 O A:HOH108 2.2 17.2 1.0 OP1 B:C4315 4.2 21.6 1.0 OP1 A:C433 4.3 24.8 1.0 O B:HOH130 4.4 24.8 1.0 OP1 A:G484 4.4 19.6 1.0 OP2 A:G484 4.4 17.2 1.0 P A:G484 4.8 17.6 1.0

M.Teplova, G.Minasov, V.Tereshko, G.B.Inamati, P.D.Cook, M.Manoharan, M.Egli. Crystal Structure and Improved Antisense Properties of 2'-O-(2-Methoxyethyl)-Rna. Nat.Struct.Biol. V. 6 535 1999.
ISSN: ISSN 1072-8368
PubMed: 10360355
DOI: 10.1038/9304