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Atomistry » Magnesium » PDB 3zx4-4a28 » 4a07 | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 3zx4-4a28 » 4a07 » |
Magnesium in PDB 4a07: Human PDK1 Kinase Domain in Complex with Allosteric Activator PS171 Bound to the Pif-PocketEnzymatic activity of Human PDK1 Kinase Domain in Complex with Allosteric Activator PS171 Bound to the Pif-Pocket
All present enzymatic activity of Human PDK1 Kinase Domain in Complex with Allosteric Activator PS171 Bound to the Pif-Pocket:
2.7.11.1; Protein crystallography data
The structure of Human PDK1 Kinase Domain in Complex with Allosteric Activator PS171 Bound to the Pif-Pocket, PDB code: 4a07
was solved by
J.O.Schulze,
L.A.Lopez-Garcia,
W.Froehner,
H.Zhang,
J.Navratil,
V.Hindie,
S.Zeuzem,
P.M.Alzari,
S.Neimanis,
M.Engel,
R.M.Biondi,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4a07:
The structure of Human PDK1 Kinase Domain in Complex with Allosteric Activator PS171 Bound to the Pif-Pocket also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the Human PDK1 Kinase Domain in Complex with Allosteric Activator PS171 Bound to the Pif-Pocket
(pdb code 4a07). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Human PDK1 Kinase Domain in Complex with Allosteric Activator PS171 Bound to the Pif-Pocket, PDB code: 4a07: Magnesium binding site 1 out of 1 in 4a07Go back to Magnesium Binding Sites List in 4a07
Magnesium binding site 1 out
of 1 in the Human PDK1 Kinase Domain in Complex with Allosteric Activator PS171 Bound to the Pif-Pocket
Mono view Stereo pair view
Reference:
L.A.Lopez-Garcia,
J.O.Schulze,
W.Frohner,
H.Zhang,
E.Suss,
N.Weber,
J.Navratil,
S.Amon,
V.Hindie,
S.Zeuzem,
T.J.Jorgensen,
P.M.Alzari,
S.Neimanis,
M.Engel,
R.M.Biondi.
Allosteric Regulation of Protein Kinase Pkczeta By the N- Terminal C1 Domain and Small Compounds to the Pif-Pocket. Chem.Biol. V. 18 1463 2011.
Page generated: Mon Dec 14 09:05:30 2020
ISSN: ISSN 1074-5521 PubMed: 22118680 DOI: 10.1016/J.CHEMBIOL.2011.08.010 |
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