Magnesium in PDB 4aqv: Model of Human Kinesin-5 Motor Domain (3HQD) and Mammalian Tubulin Heterodimer (1JFF) Docked Into the 9.7-Angstrom Cryo-Em Map of Microtubule-Bound Kinesin-5 Motor Domain in the Ampppnp State.

The binding sites of Magnesium atom in the Model of Human Kinesin-5 Motor Domain (3HQD) and Mammalian Tubulin Heterodimer (1JFF) Docked Into the 9.7-Angstrom Cryo-Em Map of Microtubule-Bound Kinesin-5 Motor Domain in the Ampppnp State. (pdb code 4aqv). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Model of Human Kinesin-5 Motor Domain (3HQD) and Mammalian Tubulin Heterodimer (1JFF) Docked Into the 9.7-Angstrom Cryo-Em Map of Microtubule-Bound Kinesin-5 Motor Domain in the Ampppnp State., PDB code: 4aqv:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Model of Human Kinesin-5 Motor Domain (3HQD) and Mammalian Tubulin Heterodimer (1JFF) Docked Into the 9.7-Angstrom Cryo-Em Map of Microtubule-Bound Kinesin-5 Motor Domain in the Ampppnp State.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Model of Human Kinesin-5 Motor Domain (3HQD) and Mammalian Tubulin Heterodimer (1JFF) Docked Into the 9.7-Angstrom Cryo-Em Map of Microtubule-Bound Kinesin-5 Motor Domain in the Ampppnp State. within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg500 b:18.6 occ:1.00 O2G A:GTP501 2.4 28.7 1.0 O2B A:GTP501 3.2 41.2 1.0 PG A:GTP501 3.7 30.0 1.0 O3B A:GTP501 3.7 35.2 1.0 PB A:GTP501 3.8 41.4 1.0 CA A:GLN11 3.9 23.8 1.0 O3A A:GTP501 4.1 39.2 1.0 O1A A:GTP501 4.4 44.5 1.0 O3G A:GTP501 4.5 35.0 1.0 PA A:GTP501 4.8 41.3 1.0 O1G A:GTP501 4.9 32.1 1.0

Magnesium binding site 2 out of 2 in the Model of Human Kinesin-5 Motor Domain (3HQD) and Mammalian Tubulin Heterodimer (1JFF) Docked Into the 9.7-Angstrom Cryo-Em Map of Microtubule-Bound Kinesin-5 Motor Domain in the Ampppnp State.


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Model of Human Kinesin-5 Motor Domain (3HQD) and Mammalian Tubulin Heterodimer (1JFF) Docked Into the 9.7-Angstrom Cryo-Em Map of Microtubule-Bound Kinesin-5 Motor Domain in the Ampppnp State. within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg501 b:14.2 occ:1.00 O2B C:ANP500 2.1 15.1 1.0 O2G C:ANP500 2.2 13.1 1.0 PB C:ANP500 3.4 14.3 1.0 PG C:ANP500 3.5 17.2 1.0 CA C:SER233 3.7 11.7 1.0 N3B C:ANP500 3.9 16.2 1.0 O1G C:ANP500 4.2 18.1 1.0 CA C:THR112 4.3 10.6 1.0 O1B C:ANP500 4.3 11.3 1.0 O2A C:ANP500 4.4 17.3 1.0 O3A C:ANP500 4.5 18.2 1.0 O3G C:ANP500 4.7 21.1 1.0 PA C:ANP500 4.8 20.0 1.0 CA C:SER232 4.9 13.4 1.0

A.Goulet, W.M.Behnke-Parks, C.V.Sindelar, J.Major, S.S.Rosenfeld, C.Moores. The Structural Basis of Force Generation By the Mitotic Motor Kinesin-5. J.Biol.Chem. V. 287 44654 2012.
ISSN: ISSN 0021-9258
PubMed: 23135273
DOI: 10.1074/JBC.M112.404228