Magnesium in PDB 4c0s: Mammalian Translation Elongation Factor EEF1A2

The structure of Mammalian Translation Elongation Factor EEF1A2, PDB code: 4c0s was solved by T.Crepin, V.F.Shalak, A.D.Yaremchuk, D.O.Vlasenko, A.A.Mccarthy, B.S.Negrutskii, M.A.Tukalo, A.V.El'skaya, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	25.000 / 2.70
Space group	P 61 2 2
Cell size a, b, c (Å), α, β, γ (°)	135.370, 135.370, 304.620, 90.00, 90.00, 120.00
R / Rfree (%)	20.19 / 25.56

The binding sites of Magnesium atom in the Mammalian Translation Elongation Factor EEF1A2 (pdb code 4c0s). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the Mammalian Translation Elongation Factor EEF1A2, PDB code: 4c0s:
Jump to Magnesium binding site number: 1; 2;

Magnesium binding site 1 out of 2 in the Mammalian Translation Elongation Factor EEF1A2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Mammalian Translation Elongation Factor EEF1A2 within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg501 b:49.1 occ:1.00 O1B A:GDP500 2.5 47.4 1.0 OD1 A:ASP17 2.5 57.7 1.0 O1A A:GDP500 2.7 49.0 1.0 PB A:GDP500 3.7 40.7 1.0 O3A A:GDP500 3.7 35.8 1.0 PA A:GDP500 3.7 37.7 1.0 CG A:ASP17 3.8 55.7 1.0 O2B A:GDP500 4.2 34.5 1.0 O5' A:GDP500 4.3 31.6 1.0 O A:HOH2001 4.5 42.6 1.0 CA A:ASP17 4.5 40.0 1.0 C5' A:GDP500 4.6 34.8 1.0 OD2 A:ASP17 4.6 57.8 1.0 N A:ASP17 4.6 36.7 1.0 CB A:ASP17 4.8 39.9 1.0

Magnesium binding site 2 out of 2 in the Mammalian Translation Elongation Factor EEF1A2


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Mammalian Translation Elongation Factor EEF1A2 within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg501 b:53.9 occ:1.00 O1B B:GDP500 2.7 44.0 1.0 O1A B:GDP500 2.8 35.1 1.0 OD1 B:ASP17 3.5 53.1 1.0 O3A B:GDP500 3.6 39.0 1.0 PB B:GDP500 3.6 38.4 1.0 PA B:GDP500 3.7 38.4 1.0 O2B B:GDP500 4.0 32.2 1.0 C5' B:GDP500 4.3 49.5 1.0 O5' B:GDP500 4.5 49.2 1.0 CG B:ASP17 4.5 54.0 1.0 N B:ASP17 4.6 39.9 1.0 CA B:ASP17 4.7 41.9 1.0 O3B B:GDP500 4.9 30.5 1.0 O2A B:GDP500 5.0 44.1 1.0

T.Crepin, A.Mccarthy, A.Negrutskii, V.F.Shalak, V.Tukalo, D.O.Vlasenko, A.D.Yaremchuk. Mammalian Translation Elongation Factor EEF1A2: X-Ray Structure and New Features of Gdp/Gtp Exchange Mechanism in Higher Eukaryotes Nucleic Acids Res. 2014.
ISSN: ESSN 1362-4962
PubMed: 25326326
DOI: 10.1093/NAR/GKU974