Magnesium in PDB 4cgy: Crystal Structure of the Human Topoisomerase III Alpha-RMI1 Complex

All present enzymatic activity of Crystal Structure of the Human Topoisomerase III Alpha-RMI1 Complex:
5.99.1.2;

The structure of Crystal Structure of the Human Topoisomerase III Alpha-RMI1 Complex, PDB code: 4cgy was solved by N.Bocquet, R.D.Bunker, N.H.Thoma, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	65.49 / 2.85
Space group	P 41 21 2
Cell size a, b, c (Å), α, β, γ (°)	94.010, 94.010, 381.690, 90.00, 90.00, 90.00
R / Rfree (%)	19.73 / 23.1

The binding sites of Magnesium atom in the Crystal Structure of the Human Topoisomerase III Alpha-RMI1 Complex (pdb code 4cgy). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of the Human Topoisomerase III Alpha-RMI1 Complex, PDB code: 4cgy:

Magnesium binding site 1 out of 1 in the Crystal Structure of the Human Topoisomerase III Alpha-RMI1 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of the Human Topoisomerase III Alpha-RMI1 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1640 b:62.3 occ:1.00 O A:HOH2005 2.1 63.9 1.0 O A:HOH2006 2.1 63.1 1.0 O A:HOH2010 2.1 64.5 1.0 O A:HOH2003 2.1 62.6 1.0 O A:HOH2004 2.1 61.6 1.0 OE2 A:GLU41 2.1 83.4 1.0 CD A:GLU41 3.2 90.7 1.0 OE1 A:GLU41 3.6 88.4 1.0 OD2 A:ASP148 4.1 90.8 1.0 OD2 A:ASP150 4.3 64.3 1.0 OH A:TYR362 4.3 70.3 1.0 OE2 A:GLU352 4.3 94.9 1.0 CG A:GLU41 4.4 73.1 1.0 OD1 A:ASP150 4.5 67.5 1.0 OE1 A:GLU352 4.6 84.9 1.0 CB A:GLU152 4.8 59.1 1.0 CG A:ASP150 4.8 65.1 1.0 CD A:GLU352 4.8 0.2 1.0 CB A:ASP148 4.8 60.5 1.0 CD1 A:ILE156 4.9 51.1 1.0 CG A:ASP148 4.9 79.8 1.0

N.Bocquet, A.H.Bizard, W.Abdulrahman, N.B.Larsen, M.Faty, S.Cavadini, R.D.Bunker, S.C.Kowalczykowski, P.Cejka, I.D.Hickson, N.H.Thoma. Structural and Mechanistic Insight Into Holliday-Junction Dissolution By Topoisomerase Iiialpha and RMI1 Nat.Struct.Mol.Biol. V. 21 261 2014.
ISSN: ISSN 1545-9993
PubMed: 24509834
DOI: 10.1038/NSMB.2775