Magnesium in PDB 4cvn: Structure of the FAP7-RPS14 Complex

All present enzymatic activity of Structure of the FAP7-RPS14 Complex:
2.7.4.3;

The structure of Structure of the FAP7-RPS14 Complex, PDB code: 4cvn was solved by J.Loch, M.Blaud, S.Rety, S.Lebaron, P.Deschamps, J.Bareille, J.Jombart, J.Robert-Paganin, L.Delbos, F.Chardon, E.Zhang, C.Charenton, D.Tollervey, N.Leulliot, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	44.766 / 2.12
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	67.050, 139.550, 83.080, 90.00, 105.51, 90.00
R / Rfree (%)	17.21 / 21.25

The binding sites of Magnesium atom in the Structure of the FAP7-RPS14 Complex (pdb code 4cvn). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total 4 binding sites of Magnesium where determined in the Structure of the FAP7-RPS14 Complex, PDB code: 4cvn:
Jump to Magnesium binding site number: 1; 2; 3; 4;

Magnesium binding site 1 out of 4 in the Structure of the FAP7-RPS14 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structure of the FAP7-RPS14 Complex within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg1002 b:37.7 occ:1.00 O A:HOH2013 2.1 38.3 1.0 O1B A:ADP1001 2.1 33.6 1.0 OG1 A:THR14 2.1 34.3 1.0 O A:HOH2014 2.1 35.7 1.0 O A:HOH2012 2.2 32.6 1.0 O A:HOH2049 2.2 34.4 1.0 CB A:THR14 3.2 46.0 1.0 PB A:ADP1001 3.2 38.1 1.0 O3B A:ADP1001 3.3 28.8 1.0 N A:THR14 3.8 40.4 1.0 O2A A:ADP1001 3.9 27.0 1.0 CA A:THR14 4.0 43.6 1.0 OD2 A:ASP71 4.2 42.8 1.0 OD1 A:ASP71 4.2 34.4 1.0 O A:HOH2025 4.2 40.2 1.0 O3A A:ADP1001 4.3 38.5 1.0 O A:HOH2003 4.3 49.4 1.0 O2B A:ADP1001 4.3 38.0 1.0 CG2 A:THR14 4.3 40.1 1.0 PA A:ADP1001 4.4 37.1 1.0 NH2 A:ARG100 4.4 52.8 1.0 O A:HOH2039 4.5 32.1 1.0 O1A A:ADP1001 4.6 35.0 1.0 CB A:LYS13 4.6 30.5 1.0 CG A:ASP71 4.7 53.6 1.0 O A:HOH2011 4.7 18.1 1.0 CE A:LYS13 4.8 47.1 1.0 O A:HOH2004 4.8 55.8 1.0 C A:LYS13 4.8 54.8 1.0

Magnesium binding site 2 out of 4 in the Structure of the FAP7-RPS14 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 2 of Structure of the FAP7-RPS14 Complex within 5.0Å range: probe atom residue distance (Å) B Occ B:Mg1002 b:35.5 occ:1.00 O1B B:ADP1001 2.0 30.5 1.0 O B:HOH2008 2.0 32.9 1.0 O B:HOH2006 2.2 30.4 1.0 O B:HOH2053 2.2 33.4 1.0 O B:HOH2007 2.2 28.2 1.0 OG1 B:THR14 2.2 33.3 1.0 PB B:ADP1001 3.1 34.3 1.0 CB B:THR14 3.3 49.0 1.0 O3B B:ADP1001 3.3 32.3 1.0 N B:THR14 3.9 32.5 1.0 O2A B:ADP1001 3.9 30.4 1.0 CA B:THR14 4.2 46.3 1.0 O2B B:ADP1001 4.2 33.8 1.0 O3A B:ADP1001 4.2 41.1 1.0 OD1 B:ASP71 4.3 33.4 1.0 OD2 B:ASP71 4.3 31.9 1.0 NH2 B:ARG100 4.3 68.7 1.0 O B:HOH2040 4.4 32.5 1.0 CG2 B:THR14 4.4 36.4 1.0 PA B:ADP1001 4.4 35.9 1.0 O B:HOH2020 4.4 45.9 1.0 O B:HOH2005 4.6 18.3 1.0 O E:HOH2052 4.6 52.7 1.0 O1A B:ADP1001 4.6 45.4 1.0 CB B:LYS13 4.7 29.9 1.0 CG B:ASP71 4.8 39.8 1.0 CE B:LYS13 4.8 33.2 1.0 C B:LYS13 4.9 44.2 1.0

Magnesium binding site 3 out of 4 in the Structure of the FAP7-RPS14 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 3 of Structure of the FAP7-RPS14 Complex within 5.0Å range: probe atom residue distance (Å) B Occ C:Mg1002 b:53.2 occ:1.00 O C:HOH2041 1.9 44.9 1.0 O C:HOH2005 2.1 48.4 1.0 OG1 C:THR14 2.2 55.0 1.0 O2B C:ADP1001 2.2 52.0 1.0 O C:HOH2004 2.2 47.2 1.0 O C:HOH2006 2.3 48.6 1.0 PB C:ADP1001 3.4 59.9 1.0 CB C:THR14 3.4 54.5 1.0 O1B C:ADP1001 3.6 44.9 1.0 N C:THR14 3.9 51.8 1.0 OD1 C:ASP71 4.1 53.3 1.0 OD2 C:ASP71 4.1 56.8 1.0 CA C:THR14 4.1 56.2 1.0 O C:HOH2012 4.2 49.0 1.0 O C:HOH2010 4.2 54.2 1.0 O2A C:ADP1001 4.3 49.9 1.0 O3B C:ADP1001 4.3 91.0 1.0 O3A C:ADP1001 4.5 82.8 1.0 CG C:ASP71 4.5 67.7 1.0 CG2 C:THR14 4.5 57.6 1.0 CB C:LYS13 4.6 47.9 1.0 O1A C:ADP1001 4.7 62.4 1.0 PA C:ADP1001 4.7 63.9 1.0 CE C:LYS13 4.7 58.0 1.0 NH2 C:ARG100 4.7 77.2 1.0 O C:HOH2003 4.7 44.7 1.0 C C:LYS13 4.8 56.9 1.0 NZ C:LYS13 5.0 45.7 1.0

Magnesium binding site 4 out of 4 in the Structure of the FAP7-RPS14 Complex


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 4 of Structure of the FAP7-RPS14 Complex within 5.0Å range: probe atom residue distance (Å) B Occ D:Mg1002 b:69.2 occ:1.00 OG1 D:THR14 2.0 70.1 1.0 O D:HOH2004 2.0 50.7 1.0 O2B D:ADP1001 2.0 84.8 1.0 O D:HOH2026 2.1 45.2 1.0 O D:HOH2006 2.2 56.0 1.0 O D:HOH2005 2.3 51.2 1.0 CB D:THR14 2.9 71.3 1.0 PB D:ADP1001 3.2 51.5 1.0 O1B D:ADP1001 3.4 43.7 1.0 N D:THR14 3.5 67.0 1.0 CA D:THR14 3.8 70.9 1.0 O2A D:ADP1001 3.8 45.7 1.0 OD2 D:ASP71 4.0 77.6 1.0 CG2 D:THR14 4.1 75.5 1.0 OD1 D:ASP71 4.2 72.3 1.0 O3A D:ADP1001 4.2 81.7 1.0 PA D:ADP1001 4.2 54.3 1.0 O1A D:ADP1001 4.3 65.1 1.0 O3B D:ADP1001 4.3 56.1 1.0 CG D:ASP71 4.5 76.5 1.0 CB D:LYS13 4.5 61.1 1.0 C D:LYS13 4.6 66.2 1.0 NH2 D:ARG100 4.6 67.9 1.0 CE D:LYS13 4.9 58.4 1.0 O D:HOH2016 5.0 44.0 1.0 CA D:LYS13 5.0 62.2 1.0

J.Loch, M.Blaud, S.Rety, S.Lebaron, P.Deschamps, J.Bareille, J.Jombart, J.Robert-Paganin, L.Delbos, F.Chardon, E.Zhang, C.Charenton, D.Tollervey, N.Leulliot. Rna Mimicry By the FAP7 Adenylate Kinase in Ribosome Biogenesis Plos Biol. V. 12 01860 2014.
ISSN: ISSN 1544-9173
PubMed: 24823650
DOI: 10.1371/JOURNAL.PBIO.1001860