Magnesium in PDB 4dbq: Myosin VI D179Y (Md-INSERT2-Cam, Delta-INSERT1) Post-Rigor State

The structure of Myosin VI D179Y (Md-INSERT2-Cam, Delta-INSERT1) Post-Rigor State, PDB code: 4dbq was solved by O.Pylypenko, H.L.Sweeney, A.Houdusse, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	19.98 / 2.60
Space group	P 21 21 21
Cell size a, b, c (Å), α, β, γ (°)	73.310, 107.880, 179.950, 90.00, 90.00, 90.00
R / Rfree (%)	17 / 22.4

The structure of Myosin VI D179Y (Md-INSERT2-Cam, Delta-INSERT1) Post-Rigor State also contains other interesting chemical elements:

Fluorine	(F)	3 atoms
Calcium	(Ca)	4 atoms

The binding sites of Magnesium atom in the Myosin VI D179Y (Md-INSERT2-Cam, Delta-INSERT1) Post-Rigor State (pdb code 4dbq). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Myosin VI D179Y (Md-INSERT2-Cam, Delta-INSERT1) Post-Rigor State, PDB code: 4dbq:

Magnesium binding site 1 out of 1 in the Myosin VI D179Y (Md-INSERT2-Cam, Delta-INSERT1) Post-Rigor State


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Myosin VI D179Y (Md-INSERT2-Cam, Delta-INSERT1) Post-Rigor State within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg903 b:32.8 occ:1.00 O2B A:ADP901 2.1 34.3 1.0 O A:HOH1001 2.2 36.2 1.0 O A:HOH1002 2.2 37.2 1.0 F2 A:BEF902 2.2 37.1 1.0 OG1 A:THR158 2.2 38.1 1.0 OG A:SER204 2.3 42.2 1.0 CB A:SER204 2.9 36.3 1.0 CB A:THR158 3.2 36.7 1.0 BE A:BEF902 3.3 34.2 1.0 PB A:ADP901 3.3 53.6 1.0 O3B A:ADP901 3.5 33.4 1.0 N A:SER204 3.6 41.1 1.0 F1 A:BEF902 3.8 35.6 1.0 CA A:SER204 3.9 38.5 1.0 N A:THR158 4.0 40.0 1.0 O2A A:ADP901 4.1 32.0 1.0 OD1 A:ASP456 4.1 46.8 1.0 CA A:THR158 4.1 36.0 1.0 OD2 A:ASP456 4.2 42.5 1.0 CG2 A:THR158 4.2 37.0 1.0 O A:HOH1051 4.3 36.0 1.0 F3 A:BEF902 4.4 35.6 1.0 O3A A:ADP901 4.5 38.4 1.0 O1B A:ADP901 4.5 40.6 1.0 CG A:ASP456 4.6 47.4 1.0 O A:ASN202 4.7 44.2 1.0 PA A:ADP901 4.7 38.1 1.0 C A:SER203 4.7 45.2 1.0 ND2 A:ASN200 4.9 38.5 1.0 O1A A:ADP901 4.9 40.3 1.0 CE A:LYS157 4.9 36.7 1.0

L.Song, O.Pylypenko, Z.Yang, A.Houdusse, L.H.Sweeney. Mutations in Myosin VI That Cause A Loss of Coordination Between Heads Provide Insights Into the Structural Changes Underlying Force Generation and the Importance of Gating To Be Published.