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Atomistry » Magnesium » PDB 4d4i-4dh8 » 4dff | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Atomistry » Magnesium » PDB 4d4i-4dh8 » 4dff » |
Magnesium in PDB 4dff: The Sar Development of Dihydroimidazoisoquinoline Derivatives As Phosphodiesterase 10A Inhibitors For the Treatment of SchizophreniaEnzymatic activity of The Sar Development of Dihydroimidazoisoquinoline Derivatives As Phosphodiesterase 10A Inhibitors For the Treatment of Schizophrenia
All present enzymatic activity of The Sar Development of Dihydroimidazoisoquinoline Derivatives As Phosphodiesterase 10A Inhibitors For the Treatment of Schizophrenia:
3.1.4.17; 3.1.4.35; Protein crystallography data
The structure of The Sar Development of Dihydroimidazoisoquinoline Derivatives As Phosphodiesterase 10A Inhibitors For the Treatment of Schizophrenia, PDB code: 4dff
was solved by
G.D.Ho,
W.M.Seganish,
A.Bercovici,
D.Tulshian,
W.J.Greenlee,
R.Van Rijn,
A.Hruza,
L.Xiao,
D.Rindgen,
D.Mullins,
M.Guzzi,
X.Zhang,
C.Bleichardt,
R.Hodgson,
with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:
Other elements in 4dff:
The structure of The Sar Development of Dihydroimidazoisoquinoline Derivatives As Phosphodiesterase 10A Inhibitors For the Treatment of Schizophrenia also contains other interesting chemical elements:
Magnesium Binding Sites:
The binding sites of Magnesium atom in the The Sar Development of Dihydroimidazoisoquinoline Derivatives As Phosphodiesterase 10A Inhibitors For the Treatment of Schizophrenia
(pdb code 4dff). This binding sites where shown within
5.0 Angstroms radius around Magnesium atom.
In total 2 binding sites of Magnesium where determined in the The Sar Development of Dihydroimidazoisoquinoline Derivatives As Phosphodiesterase 10A Inhibitors For the Treatment of Schizophrenia, PDB code: 4dff: Jump to Magnesium binding site number: 1; 2; Magnesium binding site 1 out of 2 in 4dffGo back to Magnesium Binding Sites List in 4dff
Magnesium binding site 1 out
of 2 in the The Sar Development of Dihydroimidazoisoquinoline Derivatives As Phosphodiesterase 10A Inhibitors For the Treatment of Schizophrenia
Mono view Stereo pair view
Magnesium binding site 2 out of 2 in 4dffGo back to Magnesium Binding Sites List in 4dff
Magnesium binding site 2 out
of 2 in the The Sar Development of Dihydroimidazoisoquinoline Derivatives As Phosphodiesterase 10A Inhibitors For the Treatment of Schizophrenia
Mono view Stereo pair view
Reference:
G.D.Ho,
W.Michael Seganish,
A.Bercovici,
D.Tulshian,
W.J.Greenlee,
R.Van Rijn,
A.Hruza,
L.Xiao,
D.Rindgen,
D.Mullins,
M.Guzzi,
X.Zhang,
C.Bleickardt,
R.Hodgson.
The Sar Development of Dihydroimidazoisoquinoline Derivatives As Phosphodiesterase 10A Inhibitors For the Treatment of Schizophrenia. Bioorg.Med.Chem.Lett. V. 22 2585 2012.
Page generated: Thu Aug 15 17:05:33 2024
ISSN: ISSN 0960-894X PubMed: 22377514 DOI: 10.1016/J.BMCL.2012.01.113 |
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