Atomistry » Magnesium » PDB 4e7z-4egh » 4ea2
Atomistry »
  Magnesium »
    PDB 4e7z-4egh »
      4ea2 »

Magnesium in PDB 4ea2: Crystal Structure of Dehydrosqualene Synthase (Crtm) Aureus Complexed with Sq-109

Enzymatic activity of Crystal Structure of Dehydrosqualene Synthase (Crtm) Aureus Complexed with Sq-109

All present enzymatic activity of Crystal Structure of Dehydrosqualene Synthase (Crtm) Aureus Complexed with Sq-109:
2.5.1.96;

Protein crystallography data

The structure of Crystal Structure of Dehydrosqualene Synthase (Crtm) Aureus Complexed with Sq-109, PDB code: 4ea2 was solved by F.-Y.Lin, K.Li, Y.-L.Liu, E.Oldfield, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å) 34.70 / 2.05
Space group P 32 2 1
Cell size a, b, c (Å), α, β, γ (°) 80.146, 80.146, 90.861, 90.00, 90.00, 120.00
R / Rfree (%) 20.6 / 26

Magnesium Binding Sites:

The binding sites of Magnesium atom in the Crystal Structure of Dehydrosqualene Synthase (Crtm) Aureus Complexed with Sq-109 (pdb code 4ea2). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Crystal Structure of Dehydrosqualene Synthase (Crtm) Aureus Complexed with Sq-109, PDB code: 4ea2:

Magnesium binding site 1 out of 1 in 4ea2

Go back to Magnesium Binding Sites List in 4ea2
Magnesium binding site 1 out of 1 in the Crystal Structure of Dehydrosqualene Synthase (Crtm) Aureus Complexed with Sq-109


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Crystal Structure of Dehydrosqualene Synthase (Crtm) Aureus Complexed with Sq-109 within 5.0Å range:
probe atom residue distance (Å) B Occ
A:Mg303

b:75.6
occ:1.00
O A:HOH462 1.5 73.6 1.0
O A:HOH463 2.1 63.0 1.0
OH A:TYR129 3.3 55.7 1.0
OD2 A:ASP48 3.3 74.9 1.0
CG2 A:VAL133 4.2 40.1 1.0
OD2 A:ASP114 4.2 71.0 1.0
CZ A:TYR129 4.3 40.9 1.0
CG A:ASP48 4.5 64.3 1.0
CE1 A:TYR129 4.6 43.9 1.0
CG A:ASP114 4.7 69.2 1.0
CG2 A:VAL111 4.9 37.9 1.0

Reference:

F.Y.Lin, Y.L.Liu, K.Li, R.Cao, W.Zhu, J.Axelson, R.Pang, E.Oldfield. Head-to-Head Prenyl Tranferases: Anti-Infective Drug Targets. J.Med.Chem. V. 55 4367 2012.
ISSN: ISSN 0022-2623
PubMed: 22486710
DOI: 10.1021/JM300208P
Page generated: Mon Dec 14 13:48:02 2020

Last articles

Zn in 8WB0
Zn in 8WAX
Zn in 8WAU
Zn in 8WAZ
Zn in 8WAY
Zn in 8WAV
Zn in 8WAW
Zn in 8WAT
Zn in 8W7M
Zn in 8WD3
© Copyright 2008-2020 by atomistry.com
Home   |    Site Map   |    Copyright   |    Contact us   |    Privacy