Magnesium in PDB 4fl3: Structural and Biophysical Characterization of the Syk Activation Switch

All present enzymatic activity of Structural and Biophysical Characterization of the Syk Activation Switch:
2.7.10.2;

The structure of Structural and Biophysical Characterization of the Syk Activation Switch, PDB code: 4fl3 was solved by U.Graedler, D.Schwarz, V.Dresing, M.Musil, J.Bomke, M.Frech, S.Jaekel, T.Rysiok, D.Mueller-Pompalla, A.Wegener, with X-Ray Crystallography technique. A brief refinement statistics is given in the table below:

Resolution Low / High (Å)	46.23 / 1.90
Space group	P 1 21 1
Cell size a, b, c (Å), α, β, γ (°)	62.735, 71.034, 76.333, 90.00, 103.93, 90.00
R / Rfree (%)	17.8 / 20.8

The binding sites of Magnesium atom in the Structural and Biophysical Characterization of the Syk Activation Switch (pdb code 4fl3). This binding sites where shown within 5.0 Angstroms radius around Magnesium atom.
In total only one binding site of Magnesium was determined in the Structural and Biophysical Characterization of the Syk Activation Switch, PDB code: 4fl3:

Magnesium binding site 1 out of 1 in the Structural and Biophysical Characterization of the Syk Activation Switch


Mono view


Stereo pair view

A full contact list of Magnesium with other atoms in the Mg binding site number 1 of Structural and Biophysical Characterization of the Syk Activation Switch within 5.0Å range: probe atom residue distance (Å) B Occ A:Mg702 b:22.9 occ:1.00 O1B A:ANP701 2.0 39.2 1.0 O A:HOH1198 2.1 38.6 1.0 O2A A:ANP701 2.1 30.0 1.0 OD1 A:ASN499 2.2 22.4 1.0 O A:HOH1002 2.2 31.3 1.0 OD2 A:ASP512 2.3 43.8 1.0 CG A:ASP512 3.2 37.7 1.0 PB A:ANP701 3.2 38.5 1.0 PA A:ANP701 3.3 32.8 1.0 CG A:ASN499 3.4 28.3 1.0 O3A A:ANP701 3.5 35.6 1.0 O2G A:ANP701 3.7 37.2 1.0 CB A:ASP512 4.0 23.1 1.0 O5' A:ANP701 4.1 36.2 1.0 OD1 A:ASP512 4.1 35.5 1.0 ND2 A:ASN499 4.1 21.6 1.0 NZ A:LYS402 4.1 29.9 1.0 N3B A:ANP701 4.2 37.6 1.0 O A:ARG498 4.3 23.8 1.0 OG A:SER511 4.3 23.0 1.0 PG A:ANP701 4.3 38.2 1.0 O2B A:ANP701 4.3 44.8 1.0 O1G A:ANP701 4.5 43.2 1.0 O A:HOH1172 4.5 41.4 1.0 CB A:ASN499 4.5 19.6 1.0 O1A A:ANP701 4.6 29.7 1.0 CA A:ASN499 4.6 20.4 1.0 O A:HOH1013 4.6 28.6 1.0 O A:HOH927 4.8 30.8 1.0 C A:ARG498 4.9 23.8 1.0

U.Gradler, D.Schwarz, V.Dresing, D.Musil, J.Bomke, M.Frech, H.Greiner, S.Jakel, T.Rysiok, D.Muller-Pompalla, A.Wegener. Structural and Biophysical Characterization of the Syk Activation Switch. J.Mol.Biol. V. 425 309 2013.
ISSN: ISSN 0022-2836
PubMed: 23154170
DOI: 10.1016/J.JMB.2012.11.007